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Effective high-throughput RT-qPCR screening for SARS-CoV-2 infections in children.
Dewald F, Suárez I, Johnen R, Grossbach J, Moran-Tovar R, Steger G, Joachim A, Rubio GH, Fries M, Behr F, Kley J, Lingnau A, Kretschmer A, Gude C, Baeza-Flores G, Del Valle DL, Roblero-Hernandez A, Magana-Cerino J, Hernandez AT, Ruiz-Quinones J, Schega K, Linne V, Junker L, Wunsch M, Heger E, Knops E, Di Cristanziano V, Meyer M, Hünseler C, Weber LT, Lüers JC, Quade G, Wisplinghoff H, Tiemann C, Zotz R, Jomaa H, Pranada A, Herzum I, Cullen P, Schmitz FJ, Philipsen P, Kirchner G, Knabbe C, Hellmich M, Buess M, Wolff A, Kossow A, Niessen J, Jeworutzki S, Schräpler JP, Lässig M, Dötsch J, Fätkenheuer G, Kaiser R, Beyer A, Rybniker J, Klein F. Dewald F, et al. Among authors: grossbach j. Nat Commun. 2022 Jun 25;13(1):3640. doi: 10.1038/s41467-022-30664-2. Nat Commun. 2022. PMID: 35752615 Free PMC article.
Global, in situ analysis of the structural proteome in individuals with Parkinson's disease to identify a new class of biomarker.
Mackmull MT, Nagel L, Sesterhenn F, Muntel J, Grossbach J, Stalder P, Bruderer R, Reiter L, van de Berg WDJ, de Souza N, Beyer A, Picotti P. Mackmull MT, et al. Among authors: grossbach j. Nat Struct Mol Biol. 2022 Oct;29(10):978-989. doi: 10.1038/s41594-022-00837-0. Epub 2022 Oct 12. Nat Struct Mol Biol. 2022. PMID: 36224378
Insufficient evidence for non-neutrality of synonymous mutations.
Kruglyak L, Beyer A, Bloom JS, Grossbach J, Lieberman TD, Mancuso CP, Rich MS, Sherlock G, Kaplan CD. Kruglyak L, et al. Among authors: grossbach j. Nature. 2023 Apr;616(7957):E8-E9. doi: 10.1038/s41586-023-05865-4. Epub 2023 Apr 19. Nature. 2023. PMID: 37076734 No abstract available.
Genetic effects on molecular network states explain complex traits.
Weith M, Großbach J, Clement-Ziza M, Gillet L, Rodríguez-López M, Marguerat S, Workman CT, Picotti P, Bähler J, Aebersold R, Beyer A. Weith M, et al. Among authors: grossbach j. Mol Syst Biol. 2023 Aug 8;19(8):e11493. doi: 10.15252/msb.202211493. Epub 2023 Jul 24. Mol Syst Biol. 2023. PMID: 37485750 Free PMC article.
In planta expression of human polyQ-expanded huntingtin fragment reveals mechanisms to prevent disease-related protein aggregation.
Llamas E, Koyuncu S, Lee HJ, Wehrmann M, Gutierrez-Garcia R, Dunken N, Charura N, Torres-Montilla S, Schlimgen E, Mandel AM, Theile EB, Grossbach J, Wagle P, Lackmann JW, Schermer B, Benzing T, Beyer A, Pulido P, Rodriguez-Concepcion M, Zuccaro A, Vilchez D. Llamas E, et al. Among authors: grossbach j. Nat Aging. 2023 Nov;3(11):1345-1357. doi: 10.1038/s43587-023-00502-1. Epub 2023 Oct 2. Nat Aging. 2023. PMID: 37783816 Free PMC article.
Dynamic 3D proteomes reveal protein functional alterations at high resolution in situ.
Cappelletti V, Hauser T, Piazza I, Pepelnjak M, Malinovska L, Fuhrer T, Li Y, Dörig C, Boersema P, Gillet L, Grossbach J, Dugourd A, Saez-Rodriguez J, Beyer A, Zamboni N, Caflisch A, de Souza N, Picotti P. Cappelletti V, et al. Among authors: grossbach j. Cell. 2021 Jan 21;184(2):545-559.e22. doi: 10.1016/j.cell.2020.12.021. Epub 2020 Dec 23. Cell. 2021. PMID: 33357446 Free PMC article.
External Stresses Affect Gonococcal Type 4 Pilus Dynamics.
Kraus-Römer S, Wielert I, Rathmann I, Grossbach J, Maier B. Kraus-Römer S, et al. Among authors: grossbach j. Front Microbiol. 2022 Feb 25;13:839711. doi: 10.3389/fmicb.2022.839711. eCollection 2022. Front Microbiol. 2022. PMID: 35283813 Free PMC article.