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Page 1
Slow progression of pediatric HIV associates with early CD8+ T cell PD-1 expression and a stem-like phenotype.
Vieira V, Lim N, Singh A, Leitman E, Dsouza R, Adland E, Muenchhoff M, Roider J, Marin Lopez M, Carabelli J, Giandhari J, Groll A, Jooste P, Prado JG, Thobakgale C, Dong K, Kiepiela P, Prendergast AJ, Tudor-Williams G, Frater J, Walker BD, Ndung'u T, Ramsuran V, Leslie A, Kløverpris HN, Goulder P. Vieira V, et al. Among authors: groll a. JCI Insight. 2023 Feb 8;8(3):e156049. doi: 10.1172/jci.insight.156049. JCI Insight. 2023. PMID: 36602861 Free PMC article.
Nonprogressing HIV-infected children share fundamental immunological features of nonpathogenic SIV infection.
Muenchhoff M, Adland E, Karimanzira O, Crowther C, Pace M, Csala A, Leitman E, Moonsamy A, McGregor C, Hurst J, Groll A, Mori M, Sinmyee S, Thobakgale C, Tudor-Williams G, Prendergast AJ, Kloverpris H, Roider J, Leslie A, Shingadia D, Brits T, Daniels S, Frater J, Willberg CB, Walker BD, Ndung'u T, Jooste P, Moore PL, Morris L, Goulder P. Muenchhoff M, et al. Among authors: groll a. Sci Transl Med. 2016 Sep 28;8(358):358ra125. doi: 10.1126/scitranslmed.aag1048. Sci Transl Med. 2016. PMID: 27683550 Free PMC article.
Malnutrition in HIV-Infected Children Is an Indicator of Severe Disease with an Impaired Response to Antiretroviral Therapy.
Muenchhoff M, Healy M, Singh R, Roider J, Groll A, Kindra C, Sibaya T, Moonsamy A, McGregor C, Phan MQ, Palma A, Kloverpris H, Leslie A, Bobat R, LaRussa P, Ndung'u T, Goulder P, Sobieszczyk ME, Archary M. Muenchhoff M, et al. Among authors: groll a. AIDS Res Hum Retroviruses. 2018 Jan;34(1):46-55. doi: 10.1089/AID.2016.0261. Epub 2017 Sep 6. AIDS Res Hum Retroviruses. 2018. PMID: 28670966 Free PMC article.
Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection.
Adland E, Millar J, Bengu N, Muenchhoff M, Fillis R, Sprenger K, Ntlantsana V, Roider J, Vieira V, Govender K, Adamson J, Nxele N, Ochsenbauer C, Kappes J, Mori L, van Lobenstein J, Graza Y, Chinniah K, Kapongo C, Bhoola R, Krishna M, Matthews PC, Poderos RP, Lluch MC, Puertas MC, Prado JG, McKerrow N, Archary M, Ndung'u T, Groll A, Jooste P, Martinez-Picado J, Altfeld M, Goulder P. Adland E, et al. Among authors: groll a. Nat Commun. 2020 Apr 14;11(1):1767. doi: 10.1038/s41467-020-15632-y. Nat Commun. 2020. PMID: 32286302 Free PMC article.
Author Correction: Sex-specific innate immune selection of HIV-1 in utero is associated with increased female susceptibility to infection.
Adland E, Millar J, Bengu N, Muenchhoff M, Fillis R, Sprenger K, Ntlantsana V, Roider J, Vieira V, Govender K, Adamson J, Nxele N, Ochsenbauer C, Kappes J, Mori L, van Lobenstein J, Graza Y, Chinniah K, Kapongo C, Bhoola R, Krishna M, Matthews PC, Poderos RP, Lluch MC, Puertas MC, Prado JG, McKerrow N, Archary M, Ndung'u T, Groll A, Jooste P, Martinez-Picado J, Altfeld M, Goulder P. Adland E, et al. Among authors: groll a. Nat Commun. 2020 May 4;11(1):2257. doi: 10.1038/s41467-020-16215-7. Nat Commun. 2020. PMID: 32367015 Free PMC article.
HIGH-FREQUENCY failure of combination antiretroviral therapy in paediatric HIV infection is associated with unmet maternal needs causing maternal NON-ADHERENCE.
Millar JR, Bengu N, Fillis R, Sprenger K, Ntlantsana V, Vieira VA, Khambati N, Archary M, Muenchhoff M, Groll A, Grayson N, Adamson J, Govender K, Dong K, Kiepiela P, Walker BD, Bonsall D, Connor T, Bull MJ, Nxele N, Roider J, Ismail N, Adland E, Puertas MC, Martinez-Picado J, Matthews PC, Ndung'u T, Goulder P; Ucwaningo Lwabantwana Consortium. Millar JR, et al. Among authors: groll a. EClinicalMedicine. 2020 May 8;22:100344. doi: 10.1016/j.eclinm.2020.100344. eCollection 2020 May. EClinicalMedicine. 2020. PMID: 32510047 Free PMC article.
Early Initiation of Antiretroviral Therapy Following In Utero HIV Infection Is Associated With Low Viral Reservoirs but Other Factors Determine Viral Rebound.
Millar JR, Bengu N, Vieira VA, Adland E, Roider J, Muenchhoff M, Fillis R, Sprenger K, Ntlantsana V, Fatti I, Archary M, Groll A, Ismail N, García-Guerrero MC, Matthews PC, Ndung'u T, Puertas MC, Martinez-Picado J, Goulder P. Millar JR, et al. Among authors: groll a. J Infect Dis. 2021 Dec 1;224(11):1925-1934. doi: 10.1093/infdis/jiab223. J Infect Dis. 2021. PMID: 33963757 Free PMC article.
An HLA-I signature favouring KIR-educated Natural Killer cells mediates immune control of HIV in children and contrasts with the HLA-B-restricted CD8+ T-cell-mediated immune control in adults.
Vieira VA, Adland E, Malone DFG, Martin MP, Groll A, Ansari MA, Garcia-Guerrero MC, Puertas MC, Muenchhoff M, Guash CF, Brander C, Martinez-Picado J, Bamford A, Tudor-Williams G, Ndung'u T, Walker BD, Ramsuran V, Frater J, Jooste P, Peppa D, Carrington M, Goulder PJR. Vieira VA, et al. Among authors: groll a. PLoS Pathog. 2021 Nov 18;17(11):e1010090. doi: 10.1371/journal.ppat.1010090. eCollection 2021 Nov. PLoS Pathog. 2021. PMID: 34793581 Free PMC article.
401 results