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Leishmania braziliensis enhances monocyte responses to promote anti-tumor activity.
Dos Santos JC, Moreno M, Teufel LU, Chilibroste S, Keating ST, Groh L, Domínguez-Andrés J, Williams DL, Ma Z, Lowman DW, Ensley HE, Novakovic B, Ribeiro-Dias F, Netea MG, Chabalgoity JA, Joosten LAB. Dos Santos JC, et al. Among authors: groh l. Cell Rep. 2024 Mar 26;43(3):113932. doi: 10.1016/j.celrep.2024.113932. Epub 2024 Mar 7. Cell Rep. 2024. PMID: 38457336 Free PMC article.
The Set7 Lysine Methyltransferase Regulates Plasticity in Oxidative Phosphorylation Necessary for Trained Immunity Induced by β-Glucan.
Keating ST, Groh L, van der Heijden CDCC, Rodriguez H, Dos Santos JC, Fanucchi S, Okabe J, Kaipananickal H, van Puffelen JH, Helder L, Noz MP, Matzaraki V, Li Y, de Bree LCJ, Koeken VACM, Moorlag SJCFM, Mourits VP, Domínguez-Andrés J, Oosting M, Bulthuis EP, Koopman WJH, Mhlanga M, El-Osta A, Joosten LAB, Netea MG, Riksen NP. Keating ST, et al. Among authors: groh l. Cell Rep. 2020 Apr 21;31(3):107548. doi: 10.1016/j.celrep.2020.107548. Cell Rep. 2020. PMID: 32320649 Free PMC article.
Monocyte and macrophage immunometabolism in atherosclerosis.
Groh L, Keating ST, Joosten LAB, Netea MG, Riksen NP. Groh L, et al. Semin Immunopathol. 2018 Feb;40(2):203-214. doi: 10.1007/s00281-017-0656-7. Epub 2017 Oct 2. Semin Immunopathol. 2018. PMID: 28971272 Free PMC article. Review.
The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.
Domínguez-Andrés J, Novakovic B, Li Y, Scicluna BP, Gresnigt MS, Arts RJW, Oosting M, Moorlag SJCFM, Groh LA, Zwaag J, Koch RM, Ter Horst R, Joosten LAB, Wijmenga C, Michelucci A, van der Poll T, Kox M, Pickkers P, Kumar V, Stunnenberg H, Netea MG. Domínguez-Andrés J, et al. Cell Metab. 2019 Jan 8;29(1):211-220.e5. doi: 10.1016/j.cmet.2018.09.003. Epub 2018 Oct 4. Cell Metab. 2019. PMID: 30293776 Free article.
Dimethyl itaconate induces long-term innate immune responses and confers protection against infection.
Ferreira AV, Kostidis S, Groh LA, Koeken VACM, Bruno M, Baydemir I, Kilic G, Bulut Ö, Andriopoulou T, Spanou V, Synodinou KD, Gkavogianni T, Moorlag SJCFM, Charlotte de Bree L, Mourits VP, Matzaraki V, Koopman WJH, van de Veerdonk FL, Renieris G, Giera M, Giamarellos-Bourboulis EJ, Novakovic B, Domínguez-Andrés J. Ferreira AV, et al. Among authors: groh la. Cell Rep. 2023 Jun 27;42(6):112658. doi: 10.1016/j.celrep.2023.112658. Epub 2023 Jun 16. Cell Rep. 2023. PMID: 37330914 Free article.
Getting to the marrow of trained immunity.
Groh L, Netea MG, Riksen NP, Keating ST. Groh L, et al. Epigenomics. 2018 Sep;10(9):1151-1154. doi: 10.2217/epi-2018-0098. Epigenomics. 2018. PMID: 30238777 No abstract available.
Catecholamines Induce Trained Immunity in Monocytes In Vitro and In Vivo.
van der Heijden CDCC, Groh L, Keating ST, Kaffa C, Noz MP, Kersten S, van Herwaarden AE, Hoischen A, Joosten LAB, Timmers HJLM, Netea MG, Riksen NP. van der Heijden CDCC, et al. Among authors: groh l. Circ Res. 2020 Jul 3;127(2):269-283. doi: 10.1161/CIRCRESAHA.119.315800. Epub 2020 Apr 3. Circ Res. 2020. PMID: 32241223
Rewiring of glucose metabolism defines trained immunity induced by oxidized low-density lipoprotein.
Keating ST, Groh L, Thiem K, Bekkering S, Li Y, Matzaraki V, van der Heijden CDCC, van Puffelen JH, Lachmandas E, Jansen T, Oosting M, de Bree LCJ, Koeken VACM, Moorlag SJCFM, Mourits VP, van Diepen J, Strienstra R, Novakovic B, Stunnenberg HG, van Crevel R, Joosten LAB, Netea MG, Riksen NP. Keating ST, et al. Among authors: groh l. J Mol Med (Berl). 2020 Jun;98(6):819-831. doi: 10.1007/s00109-020-01915-w. Epub 2020 Apr 30. J Mol Med (Berl). 2020. PMID: 32350546 Free PMC article.
Lysine methyltransferase G9a is an important modulator of trained immunity.
Mourits VP, van Puffelen JH, Novakovic B, Bruno M, Ferreira AV, Arts RJ, Groh L, Crișan TO, Zwaag J, Jentho E, Kox M, Pickkers P, van de Veerdonk FL, Weis S, Oosterwijk E, Vermeulen SH, Netea MG, Joosten LA. Mourits VP, et al. Among authors: groh l. Clin Transl Immunology. 2021 Feb 18;10(2):e1253. doi: 10.1002/cti2.1253. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33708384 Free PMC article.
50 results