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Page 1
Genetic Models Reveal cis and trans Immune-Regulatory Activities for lincRNA-Cox2.
Elling R, Robinson EK, Shapleigh B, Liapis SC, Covarrubias S, Katzman S, Groff AF, Jiang Z, Agarwal S, Motwani M, Chan J, Sharma S, Hennessy EJ, FitzGerald GA, McManus MT, Rinn JL, Fitzgerald KA, Carpenter S. Elling R, et al. Among authors: groff af. Cell Rep. 2018 Nov 6;25(6):1511-1524.e6. doi: 10.1016/j.celrep.2018.10.027. Cell Rep. 2018. PMID: 30404006 Free PMC article.
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.
Lewandowski JP, Lee JC, Hwang T, Sunwoo H, Goldstein JM, Groff AF, Chang NP, Mallard W, Williams A, Henao-Meija J, Flavell RA, Lee JT, Gerhardinger C, Wagers AJ, Rinn JL. Lewandowski JP, et al. Among authors: groff af. Nat Commun. 2019 Nov 13;10(1):5137. doi: 10.1038/s41467-019-12970-4. Nat Commun. 2019. PMID: 31723143 Free PMC article.
The Tug1 lncRNA locus is essential for male fertility.
Lewandowski JP, Dumbović G, Watson AR, Hwang T, Jacobs-Palmer E, Chang N, Much C, Turner KM, Kirby C, Rubinstein ND, Groff AF, Liapis SC, Gerhardinger C, Bester A, Pandolfi PP, Clohessy JG, Hoekstra HE, Sauvageau M, Rinn JL. Lewandowski JP, et al. Among authors: groff af. Genome Biol. 2020 Sep 7;21(1):237. doi: 10.1186/s13059-020-02081-5. Genome Biol. 2020. PMID: 32894169 Free PMC article.
Multiple knockout mouse models reveal lincRNAs are required for life and brain development.
Sauvageau M, Goff LA, Lodato S, Bonev B, Groff AF, Gerhardinger C, Sanchez-Gomez DB, Hacisuleyman E, Li E, Spence M, Liapis SC, Mallard W, Morse M, Swerdel MR, D'Ecclessis MF, Moore JC, Lai V, Gong G, Yancopoulos GD, Frendewey D, Kellis M, Hart RP, Valenzuela DM, Arlotta P, Rinn JL. Sauvageau M, et al. Among authors: groff af. Elife. 2013 Dec 31;2:e01749. doi: 10.7554/eLife.01749. Elife. 2013. PMID: 24381249 Free PMC article.
RNA-seq as a tool for evaluating human embryo competence.
Groff AF, Resetkova N, DiDomenico F, Sakkas D, Penzias A, Rinn JL, Eggan K. Groff AF, et al. Genome Res. 2019 Oct;29(10):1705-1718. doi: 10.1101/gr.252981.119. Epub 2019 Sep 23. Genome Res. 2019. PMID: 31548358 Free PMC article.
Control of somatic tissue differentiation by the long non-coding RNA TINCR.
Kretz M, Siprashvili Z, Chu C, Webster DE, Zehnder A, Qu K, Lee CS, Flockhart RJ, Groff AF, Chow J, Johnston D, Kim GE, Spitale RC, Flynn RA, Zheng GX, Aiyer S, Raj A, Rinn JL, Chang HY, Khavari PA. Kretz M, et al. Among authors: groff af. Nature. 2013 Jan 10;493(7431):231-5. doi: 10.1038/nature11661. Epub 2012 Dec 2. Nature. 2013. PMID: 23201690 Free PMC article.
Resolving mechanisms of immune-mediated disease in primary CD4 T cells.
Bourges C, Groff AF, Burren OS, Gerhardinger C, Mattioli K, Hutchinson A, Hu T, Anand T, Epping MW, Wallace C, Smith KG, Rinn JL, Lee JC. Bourges C, et al. Among authors: groff af. EMBO Mol Med. 2020 May 8;12(5):e12112. doi: 10.15252/emmm.202012112. Epub 2020 Apr 1. EMBO Mol Med. 2020. PMID: 32239644 Free PMC article.
Spatiotemporal expression and transcriptional perturbations by long noncoding RNAs in the mouse brain.
Goff LA, Groff AF, Sauvageau M, Trayes-Gibson Z, Sanchez-Gomez DB, Morse M, Martin RD, Elcavage LE, Liapis SC, Gonzalez-Celeiro M, Plana O, Li E, Gerhardinger C, Tomassy GS, Arlotta P, Rinn JL. Goff LA, et al. Among authors: groff af. Proc Natl Acad Sci U S A. 2015 Jun 2;112(22):6855-62. doi: 10.1073/pnas.1411263112. Proc Natl Acad Sci U S A. 2015. PMID: 26034286 Free PMC article.
12 results