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Acquired resistance to anti-PD1 therapy in patients with NSCLC associates with immunosuppressive T cell phenotype.
Hiltbrunner S, Cords L, Kasser S, Freiberger SN, Kreutzer S, Toussaint NC, Grob L, Opitz I, Messerli M, Zoche M, Soltermann A, Rechsteiner M, van den Broek M, Bodenmiller B, Curioni-Fontecedro A. Hiltbrunner S, et al. Among authors: grob l. Nat Commun. 2023 Aug 24;14(1):5154. doi: 10.1038/s41467-023-40745-5. Nat Commun. 2023. PMID: 37620318 Free PMC article.
scROSHI: robust supervised hierarchical identification of single cells.
Prummer M, Bertolini A, Bosshard L, Barkmann F, Yates J, Boeva V; Tumor Profiler Consortium; Stekhoven D, Singer F. Prummer M, et al. NAR Genom Bioinform. 2023 Jun 16;5(2):lqad058. doi: 10.1093/nargab/lqad058. eCollection 2023 Jun. NAR Genom Bioinform. 2023. PMID: 37332656 Free PMC article.
Analysis of bi-atrial function using CMR feature tracking and long-axis shortening approaches in patients with diastolic dysfunction and atrial fibrillation.
Guensch DP, Kuganathan S, Utz CD, Neuenschwander MD, Grob L, Becker P, Oeri S, Huber AT, Berto MB, Spano G, Gräni C, Friedrich MG, Eberle B, Fischer K. Guensch DP, et al. Among authors: grob l. Eur Radiol. 2023 Oct;33(10):7226-7237. doi: 10.1007/s00330-023-09663-4. Epub 2023 May 5. Eur Radiol. 2023. PMID: 37145149 Free PMC article.
Low level of antioxidant capacity biomarkers but not target overexpression predicts vulnerability to ROS-inducing drugs.
Samarin J, Fabrowski P, Kurilov R, Nuskova H, Hummel-Eisenbeiss J, Pink H, Li N, Weru V, Alborzinia H, Yildiz U, Grob L, Taubert M, Czech M, Morgen M, Brandstädter C, Becker K, Mao L, Jayavelu AK, Goncalves A, Uhrig U, Seiler J, Lyu Y, Diederichs S, Klingmüller U, Muckenthaler M, Kopp-Schneider A, Teleman A, Miller AK, Gunkel N. Samarin J, et al. Among authors: grob l. Redox Biol. 2023 Jun;62:102639. doi: 10.1016/j.redox.2023.102639. Epub 2023 Feb 23. Redox Biol. 2023. PMID: 36958250 Free PMC article.
ROS Induction Targets Persister Cancer Cells with Low Metabolic Activity in NRAS-Mutated Melanoma.
Eichhoff OM, Stoffel CI, Käsler J, Briker L, Turko P, Karsai G, Zila N, Paulitschke V, Cheng PF, Leitner A, Bileck A, Zamboni N, Irmisch A, Balazs Z, Tastanova A, Pascoal S, Johansen P, Wegmann R, Mena J, Othman A, Viswanathan VS, Wenzina J, Aloia A, Saltari A, Dzung A; TuPro Consortium; Krauthammer M, Schreiber SL, Hornemann T, Distel M, Snijder B, Dummer R, Levesque MP. Eichhoff OM, et al. Cancer Res. 2023 Apr 4;83(7):1128-1146. doi: 10.1158/0008-5472.CAN-22-1826. Cancer Res. 2023. PMID: 36946761
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