Grimsey NL - Search Results

1

Novel Cannabinoid Receptor 2 (CB2) Low Lipophilicity Agonists Produce Distinct cAMP and Arrestin Signalling Kinetics without Bias.

Sharma R, Singh S, Whiting ZM, Molitor M, Vernall AJ, Grimsey NL. Sharma R, et al. Among authors: grimsey nl. Int J Mol Sci. 2023 Mar 29;24(7):6406. doi: 10.3390/ijms24076406. Int J Mol Sci. 2023. PMID: 37047385 Free PMC article.

2

Cannabinoid Receptor 2 Signalling Bias Elicited by 2,4,6-Trisubstituted 1,3,5-Triazines.

Oyagawa CRM, de la Harpe SM, Saroz Y, Glass M, Vernall AJ, Grimsey NL. Oyagawa CRM, et al. Among authors: grimsey nl. Front Pharmacol. 2018 Nov 20;9:1202. doi: 10.3389/fphar.2018.01202. eCollection 2018. Front Pharmacol. 2018. PMID: 30524271 Free PMC article.

3

Development of selective, fluorescent cannabinoid type 2 receptor ligands based on a 1,8-naphthyridin-2-(1H)-one-3-carboxamide scaffold.

Cooper AG, Oyagawa CRM, Manning JJ, Singh S, Hook S, Grimsey NL, Glass M, Tyndall JDA, Vernall AJ. Cooper AG, et al. Among authors: grimsey nl. Medchemcomm. 2018 Oct 23;9(12):2055-2067. doi: 10.1039/c8md00448j. eCollection 2018 Dec 1. Medchemcomm. 2018. PMID: 30647881 Free PMC article.

4

Chromenopyrazole-based High Affinity, Selective Fluorescent Ligands for Cannabinoid Type 2 Receptor.

Singh S, Oyagawa CRM, Macdonald C, Grimsey NL, Glass M, Vernall AJ. Singh S, et al. Among authors: grimsey nl. ACS Med Chem Lett. 2019 Jan 30;10(2):209-214. doi: 10.1021/acsmedchemlett.8b00597. eCollection 2019 Feb 14. ACS Med Chem Lett. 2019. PMID: 30783505 Free PMC article.

5

Cannabinoid CB1 and CB2 Receptor-Mediated Arrestin Translocation: Species, Subtype, and Agonist-Dependence.

Ibsen MS, Finlay DB, Patel M, Javitch JA, Glass M, Grimsey NL. Ibsen MS, et al. Among authors: grimsey nl. Front Pharmacol. 2019 Apr 10;10:350. doi: 10.3389/fphar.2019.00350. eCollection 2019. Front Pharmacol. 2019. PMID: 31024316 Free PMC article.

6

Developing the Cannabinoid Receptor 2 (CB2) pharmacopoeia: past, present, and future.

Whiting ZM, Yin J, de la Harpe SM, Vernall AJ, Grimsey NL. Whiting ZM, et al. Among authors: grimsey nl. Trends Pharmacol Sci. 2022 Sep;43(9):754-771. doi: 10.1016/j.tips.2022.06.010. Epub 2022 Jul 26. Trends Pharmacol Sci. 2022. PMID: 35906103 Review.

7

Evaluating signaling bias for synthetic cannabinoid receptor agonists at the cannabinoid CB₂ receptor.

Patel M, Grimsey NL, Banister SD, Finlay DB, Glass M. Patel M, et al. Among authors: grimsey nl. Pharmacol Res Perspect. 2023 Dec;11(6):e01157. doi: 10.1002/prp2.1157. Pharmacol Res Perspect. 2023. PMID: 38018694 Free PMC article.

8

Real-time characterization of cannabinoid receptor 1 (CB1 ) allosteric modulators reveals novel mechanism of action.

Cawston EE, Redmond WJ, Breen CM, Grimsey NL, Connor M, Glass M. Cawston EE, et al. Among authors: grimsey nl. Br J Pharmacol. 2013 Oct;170(4):893-907. doi: 10.1111/bph.12329. Br J Pharmacol. 2013. PMID: 23937487 Free PMC article.

9

Gα_s signalling of the CB₁ receptor and the influence of receptor number.

Finlay DB, Cawston EE, Grimsey NL, Hunter MR, Korde A, Vemuri VK, Makriyannis A, Glass M. Finlay DB, et al. Among authors: grimsey nl. Br J Pharmacol. 2017 Aug;174(15):2545-2562. doi: 10.1111/bph.13866. Epub 2017 Jun 19. Br J Pharmacol. 2017. PMID: 28516479 Free PMC article.

10

Real-Time Measurement of Cannabinoid Receptor-Mediated cAMP Signaling.

Hunter MR, Finlay DB, Macdonald CE, Cawston EE, Grimsey NL, Glass M. Hunter MR, et al. Among authors: grimsey nl. Methods Enzymol. 2017;593:43-59. doi: 10.1016/bs.mie.2017.05.001. Epub 2017 Jun 27. Methods Enzymol. 2017. PMID: 28750814

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