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Novel S1P(1) receptor agonists--part 3: from thiophenes to pyridines.
J Med Chem. 2014 Jan 9;57(1):110-30. doi: 10.1021/jm4014696. Epub 2013 Dec 24.
J Med Chem. 2014.
PMID: 24367923
Inhibitors of Plasmepsin II-potential antimalarial agents.
Corminboeuf O, Dunet G, Hafsi M, Grimont J, Grisostomi C, Meyer S, Binkert C, Bur D, Jones A, Prade L, Brun R, Boss C.
Corminboeuf O, et al. Among authors: grimont j.
Bioorg Med Chem Lett. 2006 Dec 15;16(24):6194-9. doi: 10.1016/j.bmcl.2006.09.027. Epub 2006 Sep 26.
Bioorg Med Chem Lett. 2006.
PMID: 17000102
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CYP3A4 Catalyzes the Rearrangement of the Dual Orexin Receptor Antagonist Daridorexant to 4-Hydroxypiperidinol Metabolites.
Treiber A, Aissaoui H, Delahaye S, Glutz S, Grimont J, Müller C, Seeland S, Siefken V, Boss C.
Treiber A, et al. Among authors: grimont j.
ChemMedChem. 2023 May 16;18(10):e202300030. doi: 10.1002/cmdc.202300030. Epub 2023 Apr 12.
ChemMedChem. 2023.
PMID: 36892179
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Metabolism of the Dual Orexin Receptor Antagonist ACT-541468, Based on Microtracer/ Accelerator Mass Spectrometry.
Muehlan C, Fischer H, Zimmer D, Aissaoui H, Grimont J, Boss C, Croft M, van Gerven J, Krähenbühl S, Dingemanse J.
Muehlan C, et al. Among authors: grimont j.
Curr Drug Metab. 2019;20(4):254-265. doi: 10.2174/1389200220666190206141814.
Curr Drug Metab. 2019.
PMID: 30727881
Clinical Trial.
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