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SIRT5 rs12216101 T>G variant is associated with liver damage and mitochondrial dysfunction in patients with non-alcoholic fatty liver disease.
Salomone F, Pipitone RM, Longo M, Malvestiti F, Amorini AM, Distefano A, Casirati E, Ciociola E, Iraci N, Leggio L, Zito R, Vicario N, Saoca C, Pennisi G, Cabibi D, Lazzarino G, Fracanzani AL, Dongiovanni P, Valenti L, Petta S, Volti GL, Grimaudo S. Salomone F, et al. Among authors: grimaudo s. J Hepatol. 2024 Jan;80(1):10-19. doi: 10.1016/j.jhep.2023.09.020. Epub 2023 Oct 25. J Hepatol. 2024. PMID: 37890719
Studies on the apoptotic activity of natural and synthetic retinoids: discovery of a new class of synthetic terphenyls that potently support cell growth and inhibit apoptosis in neuronal and HL-60 cells.
Simoni D, Giannini G, Roberti M, Rondanin R, Baruchello R, Rossi M, Grisolia G, Invidiata FP, Aiello S, Marino S, Cavallini S, Siniscalchi A, Gebbia N, Crosta L, Grimaudo S, Abbadessa V, Di Cristina A, Tolomeo M. Simoni D, et al. Among authors: grimaudo s. J Med Chem. 2005 Jun 30;48(13):4293-9. doi: 10.1021/jm049080y. J Med Chem. 2005. PMID: 15974583
Programmed cell death (PCD) associated with the stilbene motif of arotinoids: discovery of novel apoptosis inducer agents possessing activity on multidrug resistant tumor cells.
Simoni D, Roberti M, Invidiata FP, Rondanin R, Baruchello R, Malagutti C, Mazzali A, Rossi M, Grimaudo S, Dusonchet L, Meli M, Raimondi MV, D'Alessandro N, Tolomeo M. Simoni D, et al. Among authors: grimaudo s. Bioorg Med Chem Lett. 2000 Dec 4;10(23):2669-73. doi: 10.1016/s0960-894x(00)00547-3. Bioorg Med Chem Lett. 2000. PMID: 11128648
Synthesis and biological evaluation of 2- and 3-aminobenzo[b]thiophene derivatives as antimitotic agents and inhibitors of tubulin polymerization.
Romagnoli R, Baraldi PG, Carrion MD, Lopez Cara C, Preti D, Fruttarolo F, Pavani MG, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Balzarini J, Hadfield JA, Brancale A, Hamel E. Romagnoli R, et al. Among authors: grimaudo s. J Med Chem. 2007 May 3;50(9):2273-7. doi: 10.1021/jm070050f. Epub 2007 Apr 10. J Med Chem. 2007. PMID: 17419607
Stilbene-based anticancer agents: resveratrol analogues active toward HL60 leukemic cells with a non-specific phase mechanism.
Simoni D, Roberti M, Invidiata FP, Aiello E, Aiello S, Marchetti P, Baruchello R, Eleopra M, Di Cristina A, Grimaudo S, Gebbia N, Crosta L, Dieli F, Tolomeo M. Simoni D, et al. Among authors: grimaudo s. Bioorg Med Chem Lett. 2006 Jun 15;16(12):3245-8. doi: 10.1016/j.bmcl.2006.03.028. Epub 2006 Mar 31. Bioorg Med Chem Lett. 2006. PMID: 16580204
Synthesis and biological evaluation of 1-methyl-2-(3',4',5'-trimethoxybenzoyl)-3-aminoindoles as a new class of antimitotic agents and tubulin inhibitors.
Romagnoli R, Baraldi PG, Sarkar T, Carrion MD, Cara CL, Cruz-Lopez O, Preti D, Tabrizi MA, Tolomeo M, Grimaudo S, Di Cristina A, Zonta N, Balzarini J, Brancale A, Hsieh HP, Hamel E. Romagnoli R, et al. Among authors: grimaudo s. J Med Chem. 2008 Mar 13;51(5):1464-8. doi: 10.1021/jm7011547. Epub 2008 Feb 9. J Med Chem. 2008. PMID: 18260616
130 results