Griffin JH - Search Results

1

An orthosteric/allosteric bivalent peptide agonist comprising covalently linked protease activated receptor-derived peptides mimics in vitro and in vivo activities of activated protein C.

Healy LD, Fernández JA, Aiolfi R, Mosnier LO, Griffin JH. Healy LD, et al. Among authors: griffin jh. J Thromb Haemost. 2024 Apr 24:S1538-7836(24)00225-3. doi: 10.1016/j.jtha.2024.04.007. Online ahead of print. J Thromb Haemost. 2024. PMID: 38670314 Free article.

2

Biased agonism of protease-activated receptor-1 regulates thrombo-inflammation in murine sickle cell disease.

Ramadas N, Lowder K, Dutton J, Trebak F, Faes C, Griffin JH, Pawlinski R, Mosnier LO, Sparkenbaugh EM. Ramadas N, et al. Among authors: griffin jh. Blood Adv. 2024 Apr 19:bloodadvances.2023011907. doi: 10.1182/bloodadvances.2023011907. Online ahead of print. Blood Adv. 2024. PMID: 38640339

3

Retraction Note: Tissue plasminogen activator neurovascular toxicity is controlled by activated protein C.

Liu D, Cheng T, Guo H, Fernández JA, Griffin JH, Song X, Zlokovic BV. Liu D, et al. Among authors: griffin jh. Nat Med. 2024 Apr;30(4):1214. doi: 10.1038/s41591-024-02916-9. Nat Med. 2024. PMID: 38509331 No abstract available.

4

Editorial Expression of Concern: Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage.

Cheng T, Petraglia AL, Li Z, Thiyagarajan M, Zhong Z, Wu Z, Liu D, Maggirwar SB, Deane R, Fernández JA, LaRue B, Griffin JH, Chopp M, Zlokovic BV. Cheng T, et al. Among authors: griffin jh. Nat Med. 2024 Mar 20. doi: 10.1038/s41591-024-02911-0. Online ahead of print. Nat Med. 2024. PMID: 38509330 No abstract available.

5

Endothelial Protein C Receptor and 3K3A-Activated Protein C Protect Mice from Allergic Contact Dermatitis in a Contact Hypersensitivity Model.

Xue M, Jackson CJ, Lin H, Zhao R, Liang HPH, Weiler H, Griffin JH, March L. Xue M, et al. Among authors: griffin jh. Int J Mol Sci. 2024 Jan 19;25(2):1255. doi: 10.3390/ijms25021255. Int J Mol Sci. 2024. PMID: 38279255 Free PMC article.

6

A recombinant signalling-selective activated protein C that lacks anticoagulant activity is efficacious and safe in cutaneous wound preclinical models.

Zhao R, Xue M, Lin H, Smith M, Liang H, Weiler H, Griffin JH, Jackson CJ. Zhao R, et al. Among authors: griffin jh. Wound Repair Regen. 2024 Jan-Feb;32(1):90-103. doi: 10.1111/wrr.13148. Epub 2024 Jan 3. Wound Repair Regen. 2024. PMID: 38155595

7

Activated Protein C Prevents Neuronal Apoptosis via Protease Activated Receptors 1 and 3.

Guo H, Liu D, Gelbard H, Cheng T, Insalaco R, Fernández JA, Griffin JH, Zlokovic BV. Guo H, et al. Among authors: griffin jh. Neuron. 2023 Dec 20;111(24):4116. doi: 10.1016/j.neuron.2023.12.001. Epub 2023 Dec 5. Neuron. 2023. PMID: 38135361 No abstract available.

8

APC-PAR1-R46 signaling limits CXCL1 expression during poly IC-induced airway inflammation in mice.

Sharma S, Ursery LT, Bharathi V, Miles SD, Williams WA, Elzawam AZ, Schmedes CM, Egnatz GJ, Fernandez JA, Palumbo JS, Griffin JH, Mackman N, Antoniak S. Sharma S, et al. Among authors: griffin jh. J Thromb Haemost. 2023 Nov;21(11):3279-3282. doi: 10.1016/j.jtha.2023.08.018. Epub 2023 Aug 25. J Thromb Haemost. 2023. PMID: 37634652 No abstract available.

9

3K3A-Activated Protein C Inhibits Choroidal Neovascularization Growth and Leakage and Reduces NLRP3 Inflammasome, IL-1β, and Inflammatory Cell Accumulation in the Retina.

Weinberger Y, Budnik I, Nisgav Y, Palevski D, Ben-David G, Fernández JA, Margalit SN, Levy-Mendelovich S, Kenet G, Weinberger D, Griffin JH, Livnat T. Weinberger Y, et al. Among authors: griffin jh. Int J Mol Sci. 2023 Jun 26;24(13):10642. doi: 10.3390/ijms241310642. Int J Mol Sci. 2023. PMID: 37445820 Free PMC article.

10

Analysis of brain edema in RHAPSODY.

Schleicher RL, Vorasayan P, McCabe ME, Bevers MB, Davis TP, Griffin JH, Hinduja A, Jadhav AP, Lee JM, Sawyer RN Jr, Zlokovic BV, Sheth KN, Fedler JK, Lyden P, Kimberly WT; NN104 Investigators. Schleicher RL, et al. Among authors: griffin jh. Int J Stroke. 2024 Jan;19(1):68-75. doi: 10.1177/17474930231187268. Epub 2023 Jul 16. Int J Stroke. 2024. PMID: 37382409

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