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MYT1L haploinsufficiency in human neurons and mice causes autism-associated phenotypes that can be reversed by genetic and pharmacologic intervention.
Mol Psychiatry. 2023 May;28(5):2122-2135. doi: 10.1038/s41380-023-01959-7. Epub 2023 Feb 14.
Mol Psychiatry. 2023.
PMID: 36782060
Free PMC article.
Pro-neuronal activity of Myod1 due to promiscuous binding to neuronal genes.
Lee QY, Mall M, Chanda S, Zhou B, Sharma KS, Schaukowitch K, Adrian-Segarra JM, Grieder SD, Kareta MS, Wapinski OL, Ang CE, Li R, Südhof TC, Chang HY, Wernig M.
Lee QY, et al. Among authors: grieder sd.
Nat Cell Biol. 2020 Apr;22(4):401-411. doi: 10.1038/s41556-020-0490-3. Epub 2020 Mar 30.
Nat Cell Biol. 2020.
PMID: 32231311
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Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates.
Mall M, Kareta MS, Chanda S, Ahlenius H, Perotti N, Zhou B, Grieder SD, Ge X, Drake S, Euong Ang C, Walker BM, Vierbuchen T, Fuentes DR, Brennecke P, Nitta KR, Jolma A, Steinmetz LM, Taipale J, Südhof TC, Wernig M.
Mall M, et al. Among authors: grieder sd.
Nature. 2017 Apr 13;544(7649):245-249. doi: 10.1038/nature21722. Epub 2017 Apr 5.
Nature. 2017.
PMID: 28379941
Free article.
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