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Leukemia-initiating cells from some acute myeloid leukemia patients with mutated nucleophosmin reside in the CD34(-) fraction.
Taussig DC, Vargaftig J, Miraki-Moud F, Griessinger E, Sharrock K, Luke T, Lillington D, Oakervee H, Cavenagh J, Agrawal SG, Lister TA, Gribben JG, Bonnet D. Taussig DC, et al. Among authors: gribben jg. Blood. 2010 Mar 11;115(10):1976-84. doi: 10.1182/blood-2009-02-206565. Epub 2010 Jan 6. Blood. 2010. PMID: 20053758 Free PMC article.
Acute myeloid leukemia does not deplete normal hematopoietic stem cells but induces cytopenias by impeding their differentiation.
Miraki-Moud F, Anjos-Afonso F, Hodby KA, Griessinger E, Rosignoli G, Lillington D, Jia L, Davies JK, Cavenagh J, Smith M, Oakervee H, Agrawal S, Gribben JG, Bonnet D, Taussig DC. Miraki-Moud F, et al. Among authors: gribben jg. Proc Natl Acad Sci U S A. 2013 Aug 13;110(33):13576-81. doi: 10.1073/pnas.1301891110. Epub 2013 Jul 30. Proc Natl Acad Sci U S A. 2013. PMID: 23901108 Free PMC article.
HIF-2α protects human hematopoietic stem/progenitors and acute myeloid leukemic cells from apoptosis induced by endoplasmic reticulum stress.
Rouault-Pierre K, Lopez-Onieva L, Foster K, Anjos-Afonso F, Lamrissi-Garcia I, Serrano-Sanchez M, Mitter R, Ivanovic Z, de Verneuil H, Gribben J, Taussig D, Rezvani HR, Mazurier F, Bonnet D. Rouault-Pierre K, et al. Among authors: gribben j. Cell Stem Cell. 2013 Nov 7;13(5):549-63. doi: 10.1016/j.stem.2013.08.011. Epub 2013 Oct 3. Cell Stem Cell. 2013. PMID: 24095676 Free article.
A niche-like culture system allowing the maintenance of primary human acute myeloid leukemia-initiating cells: a new tool to decipher their chemoresistance and self-renewal mechanisms.
Griessinger E, Anjos-Afonso F, Pizzitola I, Rouault-Pierre K, Vargaftig J, Taussig D, Gribben J, Lassailly F, Bonnet D. Griessinger E, et al. Among authors: gribben j. Stem Cells Transl Med. 2014 Apr;3(4):520-9. doi: 10.5966/sctm.2013-0166. Epub 2014 Feb 3. Stem Cells Transl Med. 2014. PMID: 24493855 Free PMC article. Clinical Trial.
Arginine deprivation using pegylated arginine deiminase has activity against primary acute myeloid leukemia cells in vivo.
Miraki-Moud F, Ghazaly E, Ariza-McNaughton L, Hodby KA, Clear A, Anjos-Afonso F, Liapis K, Grantham M, Sohrabi F, Cavenagh J, Bomalaski JS, Gribben JG, Szlosarek PW, Bonnet D, Taussig DC. Miraki-Moud F, et al. Among authors: gribben jg. Blood. 2015 Jun 25;125(26):4060-8. doi: 10.1182/blood-2014-10-608133. Epub 2015 Apr 20. Blood. 2015. PMID: 25896651 Free article.
Characteristics of human primary mantle cell lymphoma engraftment in NSG mice.
Iyengar S, Ariza-McNaughton L, Clear A, Taussig D, Auer R, Roe A, Lillington D, Iqbal S, Joel S, Gribben J, Bonnet D. Iyengar S, et al. Among authors: gribben j. Br J Haematol. 2016 Apr;173(1):165-9. doi: 10.1111/bjh.13581. Epub 2015 Jul 28. Br J Haematol. 2016. PMID: 26215849 Free PMC article. No abstract available.
Frequency and Dynamics of Leukemia-Initiating Cells during Short-term Ex Vivo Culture Informs Outcomes in Acute Myeloid Leukemia Patients.
Griessinger E, Anjos-Afonso F, Vargaftig J, Taussig DC, Lassailly F, Prebet T, Imbert V, Nebout M, Vey N, Chabannon C, Filby A, Bollet-Quivogne F, Gribben JG, Peyron JF, Bonnet D. Griessinger E, et al. Among authors: gribben jg. Cancer Res. 2016 Apr 15;76(8):2082-6. doi: 10.1158/0008-5472.CAN-15-2063. Epub 2016 Mar 9. Cancer Res. 2016. PMID: 26960976
T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments.
Hawkins ED, Duarte D, Akinduro O, Khorshed RA, Passaro D, Nowicka M, Straszkowski L, Scott MK, Rothery S, Ruivo N, Foster K, Waibel M, Johnstone RW, Harrison SJ, Westerman DA, Quach H, Gribben J, Robinson MD, Purton LE, Bonnet D, Lo Celso C. Hawkins ED, et al. Among authors: gribben j. Nature. 2016 Oct 27;538(7626):518-522. doi: 10.1038/nature19801. Epub 2016 Oct 17. Nature. 2016. PMID: 27750279 Free PMC article.
551 results