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Hypothermia is not therapeutic in a neonatal piglet model of inflammation-sensitized hypoxia-ischemia.
Martinello KA, Meehan C, Avdic-Belltheus A, Lingam I, Mutshiya T, Yang Q, Akin MA, Price D, Sokolska M, Bainbridge A, Hristova M, Tachtsidis I, Tann CJ, Peebles D, Hagberg H, Wolfs TGAM, Klein N, Kramer BW, Fleiss B, Gressens P, Golay X, Robertson NJ. Martinello KA, et al. Among authors: gressens p. Pediatr Res. 2022 May;91(6):1416-1427. doi: 10.1038/s41390-021-01584-6. Epub 2021 May 28. Pediatr Res. 2022. PMID: 34050269 Free PMC article. Clinical Trial.
Pharmacological and genetic inhibition of NADPH oxidase does not reduce brain damage in different models of perinatal brain injury in newborn mice.
Doverhag C, Keller M, Karlsson A, Hedtjarn M, Nilsson U, Kapeller E, Sarkozy G, Klimaschewski L, Humpel C, Hagberg H, Simbruner G, Gressens P, Savman K. Doverhag C, et al. Among authors: gressens p. Neurobiol Dis. 2008 Jul;31(1):133-44. doi: 10.1016/j.nbd.2008.04.003. Epub 2008 Apr 25. Neurobiol Dis. 2008. PMID: 18571099
Systemic inflammation disrupts the developmental program of white matter.
Favrais G, van de Looij Y, Fleiss B, Ramanantsoa N, Bonnin P, Stoltenburg-Didinger G, Lacaud A, Saliba E, Dammann O, Gallego J, Sizonenko S, Hagberg H, Lelièvre V, Gressens P. Favrais G, et al. Among authors: gressens p. Ann Neurol. 2011 Oct;70(4):550-65. doi: 10.1002/ana.22489. Epub 2011 Jul 27. Ann Neurol. 2011. PMID: 21796662
485 results