Grenier L - Search Results

1

A Practical and Diastereoselective Synthesis of Ketomethylene Dipeptide Isosteres of the Type AAPsi[COCH(2)]Asp.

Déziel R, Plante R, Caron V, Grenier L, Llinas-Brunet M, Duceppe JS, Malenfant E, Moss N. Déziel R, et al. Among authors: grenier l. J Org Chem. 1996 Apr 19;61(8):2901-2903. doi: 10.1021/jo951988w. J Org Chem. 1996. PMID: 11667134 No abstract available.

2

Peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase: a new class of antiviral agents.

Moss N, Beaulieu P, Duceppe JS, Ferland JM, Gauthier J, Ghiro E, Goulet S, Grenier L, Llinas-Brunet M, Plante R, et al. Moss N, et al. Among authors: grenier l. J Med Chem. 1995 Sep 1;38(18):3617-23. doi: 10.1021/jm00018a022. J Med Chem. 1995. PMID: 7658449

3

Synthesis and biological activity of atrial natriuretic factor analogues: effect of modifications to the disulfide bridge.

DiMaio J, Jaramillo J, Wernic D, Grenier L, Welchner E, Adams J. DiMaio J, et al. Among authors: grenier l. J Med Chem. 1990 Feb;33(2):661-7. doi: 10.1021/jm00164a031. J Med Chem. 1990. PMID: 2153824

4

Design, synthesis, and biological evaluation of hydroquinone derivatives of 17-amino-17-demethoxygeldanamycin as potent, water-soluble inhibitors of Hsp90.

Ge J, Normant E, Porter JR, Ali JA, Dembski MS, Gao Y, Georges AT, Grenier L, Pak RH, Patterson J, Sydor JR, Tibbitts TT, Tong JK, Adams J, Palombella VJ. Ge J, et al. Among authors: grenier l. J Med Chem. 2006 Jul 27;49(15):4606-15. doi: 10.1021/jm0603116. J Med Chem. 2006. PMID: 16854066

5

Semisynthetic cyclopamine analogues as potent and orally bioavailable hedgehog pathway antagonists.

Tremblay MR, Nevalainen M, Nair SJ, Porter JR, Castro AC, Behnke ML, Yu LC, Hagel M, White K, Faia K, Grenier L, Campbell MJ, Cushing J, Woodward CN, Hoyt J, Foley MA, Read MA, Sydor JR, Tong JK, Palombella VJ, McGovern K, Adams J. Tremblay MR, et al. Among authors: grenier l. J Med Chem. 2008 Nov 13;51(21):6646-9. doi: 10.1021/jm8008508. Epub 2008 Oct 9. J Med Chem. 2008. PMID: 18842035

6

Novel IKK inhibitors: beta-carbolines.

Castro AC, Dang LC, Soucy F, Grenier L, Mazdiyasni H, Hottelet M, Parent L, Pien C, Palombella V, Adams J. Castro AC, et al. Among authors: grenier l. Bioorg Med Chem Lett. 2003 Jul 21;13(14):2419-22. doi: 10.1016/s0960-894x(03)00408-6. Bioorg Med Chem Lett. 2003. PMID: 12824047

7

Potent and selective inhibitors of the proteasome: dipeptidyl boronic acids.

Adams J, Behnke M, Chen S, Cruickshank AA, Dick LR, Grenier L, Klunder JM, Ma YT, Plamondon L, Stein RL. Adams J, et al. Among authors: grenier l. Bioorg Med Chem Lett. 1998 Feb 17;8(4):333-8. doi: 10.1016/s0960-894x(98)00029-8. Bioorg Med Chem Lett. 1998. PMID: 9871680

8

Ceftriaxone protects against tobramycin nephrotoxicity.

Beauchamp D, Thériault G, Grenier L, Gourde P, Perron S, Bergeron Y, Fontaine L, Bergeron MG. Beauchamp D, et al. Among authors: grenier l. Antimicrob Agents Chemother. 1994 Apr;38(4):750-6. doi: 10.1128/AAC.38.4.750. Antimicrob Agents Chemother. 1994. PMID: 8031041 Free PMC article.

9

Attenuation by daptomycin of gentamicin-induced experimental nephrotoxicity.

Thibault N, Grenier L, Simard M, Bergeron MG, Beauchamp D. Thibault N, et al. Among authors: grenier l. Antimicrob Agents Chemother. 1994 May;38(5):1027-35. doi: 10.1128/AAC.38.5.1027. Antimicrob Agents Chemother. 1994. PMID: 8067733 Free PMC article.

10

Mechanistic studies on the inactivation of the proteasome by lactacystin: a central role for clasto-lactacystin beta-lactone.

Dick LR, Cruikshank AA, Grenier L, Melandri FD, Nunes SL, Stein RL. Dick LR, et al. Among authors: grenier l. J Biol Chem. 1996 Mar 29;271(13):7273-6. doi: 10.1074/jbc.271.13.7273. J Biol Chem. 1996. PMID: 8631740 Free article.

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