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The mutational landscape of SARS-CoV-2 variants diversifies T cell targets in an HLA-supertype-dependent manner.
Hamelin DJ, Fournelle D, Grenier JC, Schockaert J, Kovalchik KA, Kubiniok P, Mostefai F, Duquette JD, Saab F, Sirois I, Smith MA, Pattijn S, Soudeyns H, Decaluwe H, Hussin J, Caron E. Hamelin DJ, et al. Among authors: grenier jc. Cell Syst. 2022 Feb 16;13(2):143-157.e3. doi: 10.1016/j.cels.2021.09.013. Epub 2021 Oct 6. Cell Syst. 2022. PMID: 34637888 Free PMC article.
Patient health records and whole viral genomes from an early SARS-CoV-2 outbreak in a Quebec hospital reveal features associated with favorable outcomes.
Paré B, Rozendaal M, Morin S, Kaufmann L, Simpson SM, Poujol R, Mostefai F, Grenier JC, Xing H, Sanchez M, Yechouron A, Racette R, Hussin JG, Wolf G, Pavlov I, Smith MA. Paré B, et al. Among authors: grenier jc. PLoS One. 2021 Dec 2;16(12):e0260714. doi: 10.1371/journal.pone.0260714. eCollection 2021. PLoS One. 2021. PMID: 34855869 Free PMC article.
Population Genomics Approaches for Genetic Characterization of SARS-CoV-2 Lineages.
Mostefai F, Gamache I, N'Guessan A, Pelletier J, Huang J, Murall CL, Pesaranghader A, Gaonac'h-Lovejoy V, Hamelin DJ, Poujol R, Grenier JC, Smith M, Caron E, Craig M, Wolf G, Krishnaswamy S, Shapiro BJ, Hussin JG. Mostefai F, et al. Among authors: grenier jc. Front Med (Lausanne). 2022 Feb 21;9:826746. doi: 10.3389/fmed.2022.826746. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35265640 Free PMC article.
Differential modulation of polyunsaturated fatty acids in patients with myocardial infarction treated with ticagrelor or clopidogrel.
Samman KN, Mehanna P, Takla E, Grenier JC, Chan MY, Lopes RD, Neely ML, Wang TY, Newby LK, Becker RC, Lordkipanidzé M, Ruiz M, Hussin JG, Jolicœur EM. Samman KN, et al. Among authors: grenier jc. Cell Rep Med. 2021 Jun 4;2(6):100299. doi: 10.1016/j.xcrm.2021.100299. eCollection 2021 Jun 15. Cell Rep Med. 2021. PMID: 34195679 Free PMC article. Clinical Trial.
Whole-exome sequencing reveals a rapid change in the frequency of rare functional variants in a founding population of humans.
Casals F, Hodgkinson A, Hussin J, Idaghdour Y, Bruat V, de Maillard T, Grenier JC, Gbeha E, Hamdan FF, Girard S, Spinella JF, Larivière M, Saillour V, Healy J, Fernández I, Sinnett D, Michaud JL, Rouleau GA, Haddad E, Le Deist F, Awadalla P. Casals F, et al. Among authors: grenier jc. PLoS Genet. 2013;9(9):e1003815. doi: 10.1371/journal.pgen.1003815. Epub 2013 Sep 26. PLoS Genet. 2013. PMID: 24086152 Free PMC article.
Rare allelic forms of PRDM9 associated with childhood leukemogenesis.
Hussin J, Sinnett D, Casals F, Idaghdour Y, Bruat V, Saillour V, Healy J, Grenier JC, de Malliard T, Busche S, Spinella JF, Larivière M, Gibson G, Andersson A, Holmfeldt L, Ma J, Wei L, Zhang J, Andelfinger G, Downing JR, Mullighan CG, Awadalla P. Hussin J, et al. Among authors: grenier jc. Genome Res. 2013 Mar;23(3):419-30. doi: 10.1101/gr.144188.112. Epub 2012 Dec 5. Genome Res. 2013. PMID: 23222848 Free PMC article.
A sex-specific evolutionary interaction between ADCY9 and CETP.
Gamache I, Legault MA, Grenier JC, Sanchez R, Rhéaume E, Asgari S, Barhdadi A, Zada YF, Trochet H, Luo Y, Lecca L, Murray M, Raychaudhuri S, Tardif JC, Dubé MP, Hussin J. Gamache I, et al. Among authors: grenier jc. Elife. 2021 Oct 5;10:e69198. doi: 10.7554/eLife.69198. Elife. 2021. PMID: 34609279 Free PMC article.
Multiscale PHATE identifies multimodal signatures of COVID-19.
Kuchroo M, Huang J, Wong P, Grenier JC, Shung D, Tong A, Lucas C, Klein J, Burkhardt DB, Gigante S, Godavarthi A, Rieck B, Israelow B, Simonov M, Mao T, Oh JE, Silva J, Takahashi T, Odio CD, Casanovas-Massana A, Fournier J; Yale IMPACT Team; Farhadian S, Dela Cruz CS, Ko AI, Hirn MJ, Wilson FP, Hussin JG, Wolf G, Iwasaki A, Krishnaswamy S. Kuchroo M, et al. Among authors: grenier jc. Nat Biotechnol. 2022 May;40(5):681-691. doi: 10.1038/s41587-021-01186-x. Epub 2022 Feb 28. Nat Biotechnol. 2022. PMID: 35228707 Free PMC article.
50 results