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BCG Educates Hematopoietic Stem Cells to Generate Protective Innate Immunity against Tuberculosis.
Kaufmann E, Sanz J, Dunn JL, Khan N, Mendonça LE, Pacis A, Tzelepis F, Pernet E, Dumaine A, Grenier JC, Mailhot-Léonard F, Ahmed E, Belle J, Besla R, Mazer B, King IL, Nijnik A, Robbins CS, Barreiro LB, Divangahi M. Kaufmann E, et al. Among authors: grenier jc. Cell. 2018 Jan 11;172(1-2):176-190.e19. doi: 10.1016/j.cell.2017.12.031. Cell. 2018. PMID: 29328912 Free article.
Genetic Ancestry and Natural Selection Drive Population Differences in Immune Responses to Pathogens.
Nédélec Y, Sanz J, Baharian G, Szpiech ZA, Pacis A, Dumaine A, Grenier JC, Freiman A, Sams AJ, Hebert S, Pagé Sabourin A, Luca F, Blekhman R, Hernandez RD, Pique-Regi R, Tung J, Yotova V, Barreiro LB. Nédélec Y, et al. Among authors: grenier jc. Cell. 2016 Oct 20;167(3):657-669.e21. doi: 10.1016/j.cell.2016.09.025. Cell. 2016. PMID: 27768889 Free article.
Bacterial infection remodels the DNA methylation landscape of human dendritic cells.
Pacis A, Tailleux L, Morin AM, Lambourne J, MacIsaac JL, Yotova V, Dumaine A, Danckaert A, Luca F, Grenier JC, Hansen KD, Gicquel B, Yu M, Pai A, He C, Tung J, Pastinen T, Kobor MS, Pique-Regi R, Gilad Y, Barreiro LB. Pacis A, et al. Among authors: grenier jc. Genome Res. 2015 Dec;25(12):1801-11. doi: 10.1101/gr.192005.115. Epub 2015 Sep 21. Genome Res. 2015. PMID: 26392366 Free PMC article.
Chronic Inflammation Permanently Reshapes Tissue-Resident Immunity in Celiac Disease.
Mayassi T, Ladell K, Gudjonson H, McLaren JE, Shaw DG, Tran MT, Rokicka JJ, Lawrence I, Grenier JC, van Unen V, Ciszewski C, Dimaano M, Sayegh HE, Kumar V, Wijmenga C, Green PHR, Gokhale R, Jericho H, Semrad CE, Guandalini S, Dinner AR, Kupfer SS, Reid HH, Barreiro LB, Rossjohn J, Price DA, Jabri B. Mayassi T, et al. Among authors: grenier jc. Cell. 2019 Feb 21;176(5):967-981.e19. doi: 10.1016/j.cell.2018.12.039. Epub 2019 Feb 7. Cell. 2019. PMID: 30739797 Free PMC article.
Natural selection contributed to immunological differences between hunter-gatherers and agriculturalists.
Harrison GF, Sanz J, Boulais J, Mina MJ, Grenier JC, Leng Y, Dumaine A, Yotova V, Bergey CM, Nsobya SL, Elledge SJ, Schurr E, Quintana-Murci L, Perry GH, Barreiro LB. Harrison GF, et al. Among authors: grenier jc. Nat Ecol Evol. 2019 Aug;3(8):1253-1264. doi: 10.1038/s41559-019-0947-6. Epub 2019 Jul 29. Nat Ecol Evol. 2019. PMID: 31358949 Free PMC article.
Widespread Shortening of 3' Untranslated Regions and Increased Exon Inclusion Are Evolutionarily Conserved Features of Innate Immune Responses to Infection.
Pai AA, Baharian G, Pagé Sabourin A, Brinkworth JF, Nédélec Y, Foley JW, Grenier JC, Siddle KJ, Dumaine A, Yotova V, Johnson ZP, Lanford RE, Burge CB, Barreiro LB. Pai AA, et al. Among authors: grenier jc. PLoS Genet. 2016 Sep 30;12(9):e1006338. doi: 10.1371/journal.pgen.1006338. eCollection 2016 Sep. PLoS Genet. 2016. PMID: 27690314 Free PMC article.
Social status alters immune regulation and response to infection in macaques.
Snyder-Mackler N, Sanz J, Kohn JN, Brinkworth JF, Morrow S, Shaver AO, Grenier JC, Pique-Regi R, Johnson ZP, Wilson ME, Barreiro LB, Tung J. Snyder-Mackler N, et al. Among authors: grenier jc. Science. 2016 Nov 25;354(6315):1041-1045. doi: 10.1126/science.aah3580. Science. 2016. PMID: 27885030 Free PMC article.
Adaptive, convergent origins of the pygmy phenotype in African rainforest hunter-gatherers.
Perry GH, Foll M, Grenier JC, Patin E, Nédélec Y, Pacis A, Barakatt M, Gravel S, Zhou X, Nsobya SL, Excoffier L, Quintana-Murci L, Dominy NJ, Barreiro LB. Perry GH, et al. Among authors: grenier jc. Proc Natl Acad Sci U S A. 2014 Sep 2;111(35):E3596-603. doi: 10.1073/pnas.1402875111. Epub 2014 Aug 18. Proc Natl Acad Sci U S A. 2014. PMID: 25136101 Free PMC article.
50 results