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Cytosine base editing inhibits hepatitis B virus replication and reduces HBsAg expression in vitro and in vivo.
Smekalova EM, Martinez MG, Combe E, Kumar A, Dejene S, Leboeuf D, Chen CY, Dorkin JR, Shuang LS, Kieft S, Young L, Barrera LA, Packer MS, Ciaramella G, Testoni B, Gregoire F, Zoulim F. Smekalova EM, et al. Among authors: gregoire f. Mol Ther Nucleic Acids. 2023 Dec 27;35(1):102112. doi: 10.1016/j.omtn.2023.102112. eCollection 2024 Mar 12. Mol Ther Nucleic Acids. 2023. PMID: 38292874 Free PMC article.
Gene Editing Technologies to Target HBV cccDNA.
Martinez MG, Smekalova E, Combe E, Gregoire F, Zoulim F, Testoni B. Martinez MG, et al. Among authors: gregoire f. Viruses. 2022 Nov 28;14(12):2654. doi: 10.3390/v14122654. Viruses. 2022. PMID: 36560658 Free PMC article. Review.
Evaluation of cytosine base editing and adenine base editing as a potential treatment for alpha-1 antitrypsin deficiency.
Packer MS, Chowdhary V, Lung G, Cheng LI, Aratyn-Schaus Y, Leboeuf D, Smith S, Shah A, Chen D, Zieger M, Cafferty BJ, Yan B, Ciaramella G, Gregoire FM, Mueller C. Packer MS, et al. Among authors: gregoire fm. Mol Ther. 2022 Apr 6;30(4):1396-1406. doi: 10.1016/j.ymthe.2022.01.040. Epub 2022 Feb 2. Mol Ther. 2022. PMID: 35121111 Free PMC article.
Ezrin Is a Novel Protein Partner of Aquaporin-5 in Human Salivary Glands and Shows Altered Expression and Cellular Localization in Sjögren's Syndrome.
Chivasso C, Hagströmer CJ, Rose KL, Lhotellerie F, Leblanc L, Wang Z, Moscato S, Chevalier C, Zindy E, Martin M, Vanhollebeke B, Gregoire F, Bolaky N, Perret J, Baldini C, Soyfoo MS, Mattii L, Schey KL, Törnroth-Horsefield S, Delporte C. Chivasso C, et al. Among authors: gregoire f. Int J Mol Sci. 2021 Aug 26;22(17):9213. doi: 10.3390/ijms22179213. Int J Mol Sci. 2021. PMID: 34502121 Free PMC article.
209 results