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A comprehensive antigen production and characterisation study for easy-to-implement, specific and quantitative SARS-CoV-2 serotests.
Klausberger M, Duerkop M, Haslacher H, Wozniak-Knopp G, Cserjan-Puschmann M, Perkmann T, Lingg N, Aguilar PP, Laurent E, De Vos J, Hofner M, Holzer B, Stadler M, Manhart G, Vierlinger K, Egger M, Milchram L, Gludovacz E, Marx N, Köppl C, Tauer C, Beck J, Maresch D, Grünwald-Gruber C, Strobl F, Satzer P, Stadlmayr G, Vavra U, Huber J, Wahrmann M, Eskandary F, Breyer MK, Sieghart D, Quehenberger P, Leitner G, Strassl R, Egger AE, Irsara C, Griesmacher A, Hoermann G, Weiss G, Bellmann-Weiler R, Loeffler-Ragg J, Borth N, Strasser R, Jungbauer A, Hahn R, Mairhofer J, Hartmann B, Binder NB, Striedner G, Mach L, Weinhäusel A, Dieplinger B, Grebien F, Gerner W, Binder CJ, Grabherr R. Klausberger M, et al. Among authors: grebien f. EBioMedicine. 2021 May;67:103348. doi: 10.1016/j.ebiom.2021.103348. Epub 2021 Apr 25. EBioMedicine. 2021. PMID: 33906067 Free PMC article.
Biomolecular condensation of NUP98 fusion proteins drives leukemogenic gene expression.
Terlecki-Zaniewicz S, Humer T, Eder T, Schmoellerl J, Heyes E, Manhart G, Kuchynka N, Parapatics K, Liberante FG, Müller AC, Tomazou EM, Grebien F. Terlecki-Zaniewicz S, et al. Among authors: grebien f. Nat Struct Mol Biol. 2021 Feb;28(2):190-201. doi: 10.1038/s41594-020-00550-w. Epub 2021 Jan 21. Nat Struct Mol Biol. 2021. PMID: 33479542 Free PMC article.
Impact of Specific N-Glycan Modifications on the Use of Plant-Produced SARS-CoV-2 Antigens in Serological Assays.
Schwestka J, König-Beihammer J, Shin YJ, Vavra U, Kienzl NF, Grünwald-Gruber C, Maresch D, Klausberger M, Laurent E, Stadler M, Manhart G, Huber J, Hofner M, Vierlinger K, Weinhäusel A, Swoboda I, Binder CJ, Gerner W, Grebien F, Altmann F, Mach L, Stöger E, Strasser R. Schwestka J, et al. Among authors: grebien f. Front Plant Sci. 2021 Sep 27;12:747500. doi: 10.3389/fpls.2021.747500. eCollection 2021. Front Plant Sci. 2021. PMID: 34646292 Free PMC article.
Designed SARS-CoV-2 receptor binding domain variants form stable monomers.
Klausberger M, Kienzl NF, Stadlmayr G, Grünwald-Gruber C, Laurent E, Stadlbauer K, Stracke F, Vierlinger K, Hofner M, Manhart G, Gerner W, Grebien F, Weinhäusel A, Mach L, Wozniak-Knopp G. Klausberger M, et al. Among authors: grebien f. Biotechnol J. 2022 May;17(5):e2100422. doi: 10.1002/biot.202100422. Epub 2022 Feb 3. Biotechnol J. 2022. PMID: 35078277 Free PMC article.
Increasing test specificity without impairing sensitivity: lessons learned from SARS-CoV-2 serology.
Perkmann T, Koller T, Perkmann-Nagele N, Ozsvar-Kozma M, Eyre D, Matthews P, Bown A, Stoesser N, Breyer MK, Breyer-Kohansal R, Burghuber OC, Hartl S, Aletaha D, Sieghart D, Quehenberger P, Marculescu R, Mucher P, Radakovics A, Klausberger M, Duerkop M, Holzer B, Hartmann B, Strassl R, Leitner G, Grebien F, Gerner W, Grabherr R, Wagner OF, Binder CJ, Haslacher H. Perkmann T, et al. Among authors: grebien f. J Clin Pathol. 2023 Nov;76(11):770-777. doi: 10.1136/jcp-2022-208171. Epub 2022 Aug 30. J Clin Pathol. 2023. PMID: 36041815
CDK6 is an essential direct target of NUP98 fusion proteins in acute myeloid leukemia.
Schmoellerl J, Barbosa IAM, Eder T, Brandstoetter T, Schmidt L, Maurer B, Troester S, Pham HTT, Sagarajit M, Ebner J, Manhart G, Aslan E, Terlecki-Zaniewicz S, Van der Veen C, Hoermann G, Duployez N, Petit A, Lapillonne H, Puissant A, Itzykson R, Moriggl R, Heuser M, Meisel R, Valent P, Sexl V, Zuber J, Grebien F. Schmoellerl J, et al. Among authors: grebien f. Blood. 2020 Jul 23;136(4):387-400. doi: 10.1182/blood.2019003267. Blood. 2020. PMID: 32344427 Free PMC article.
SBNO2 is a critical mediator of STAT3-driven hematological malignancies.
Brandstoetter T, Schmoellerl J, Grausenburger R, Kollmann S, Doma E, Huuhtanen J, Klampfl T, Eder T, Grebien F, Hoermann G, Zuber J, Mustjoki S, Maurer B, Sexl V. Brandstoetter T, et al. Among authors: grebien f. Blood. 2023 Apr 13;141(15):1831-1845. doi: 10.1182/blood.2022018494. Blood. 2023. PMID: 36630607 Free PMC article.
76 results