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Immunometabolic modulation of retinal inflammation by CD36 ligand.
Mellal K, Omri S, Mulumba M, Tahiri H, Fortin C, Dorion MF, Pham H, Garcia Ramos Y, Zhang J, Pundir S, Joyal JS, Bouchard JF, Sennlaub F, Febbraio M, Hardy P, Gravel SP, Marleau S, Lubell WD, Chemtob S, Ong H. Mellal K, et al. Among authors: gravel sp. Sci Rep. 2019 Sep 9;9(1):12903. doi: 10.1038/s41598-019-49472-8. Sci Rep. 2019. PMID: 31501473 Free PMC article.
RSK Regulates PFK-2 Activity to Promote Metabolic Rewiring in Melanoma.
Houles T, Gravel SP, Lavoie G, Shin S, Savall M, Méant A, Grondin B, Gaboury L, Yoon SO, St-Pierre J, Roux PP. Houles T, et al. Among authors: gravel sp. Cancer Res. 2018 May 1;78(9):2191-2204. doi: 10.1158/0008-5472.CAN-17-2215. Epub 2018 Feb 12. Cancer Res. 2018. PMID: 29440170
Low expression of PGC-1β and other mitochondrial biogenesis modulators in melanoma is associated with growth arrest and the induction of an immunosuppressive gene expression program dependent on MEK and IRF-1.
Laurin KM, Coutu-Beaudry K, Salazar A, Méribout N, Audet-Walsh É, Gravel SP. Laurin KM, et al. Among authors: gravel sp. Cancer Lett. 2022 Aug 10;541:215738. doi: 10.1016/j.canlet.2022.215738. Epub 2022 May 18. Cancer Lett. 2022. PMID: 35594996
mTORC1 controls mitochondrial activity and biogenesis through 4E-BP-dependent translational regulation.
Morita M, Gravel SP, Chénard V, Sikström K, Zheng L, Alain T, Gandin V, Avizonis D, Arguello M, Zakaria C, McLaughlan S, Nouet Y, Pause A, Pollak M, Gottlieb E, Larsson O, St-Pierre J, Topisirovic I, Sonenberg N. Morita M, et al. Among authors: gravel sp. Cell Metab. 2013 Nov 5;18(5):698-711. doi: 10.1016/j.cmet.2013.10.001. Cell Metab. 2013. PMID: 24206664 Free article.
PGC-1α supports glutamine metabolism in breast cancer.
McGuirk S, Gravel SP, Deblois G, Papadopoli DJ, Faubert B, Wegner A, Hiller K, Avizonis D, Akavia UD, Jones RG, Giguère V, St-Pierre J. McGuirk S, et al. Among authors: gravel sp. Cancer Metab. 2013 Dec 5;1(1):22. doi: 10.1186/2049-3002-1-22. Cancer Metab. 2013. PMID: 24304688 Free PMC article.
29 results