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Treatment using vanillin-derived synthetic molecules incorporated into polymeric micelles is effective against infection caused by Leishmania amazonensis species.
Pereira IAG, Freitas CS, Câmara RSB, Jesus MM, Lage DP, Tavares GSV, Soyer TG, Ramos FF, Soares NP, Santiago SS, Martins VT, Vale DL, Pimenta BL, Ludolf F, Oliveira FM, Duarte MC, Chávez-Fumagalli MA, Costa AV, Gonçalves DU, Roatt BM, Teixeira RR, Coelho EAF. Pereira IAG, et al. Among authors: tavares gsv. Exp Parasitol. 2024 Mar 19;260:108743. doi: 10.1016/j.exppara.2024.108743. Online ahead of print. Exp Parasitol. 2024. PMID: 38513973
New synthetic molecules incorporated into polymeric micelles used for treatment against visceral leishmaniasis.
Freitas CS, Pereira IAG, Lage DP, Vale DL, Pimenta BL, Soares NP, Santiago SS, Martins VT, Câmara RSB, Jesus MM, Tavares GSV, Ramos FF, Ludolf F, Magalhães LND, Oliveira FM, Duarte MC, Chávez-Fumagalli MA, Costa AV, Roatt BM, Teixeira RR, Coelho EAF. Freitas CS, et al. Among authors: tavares gsv. Cytokine. 2024 May;177:156543. doi: 10.1016/j.cyto.2024.156543. Epub 2024 Feb 18. Cytokine. 2024. PMID: 38373365
Immunization with recombinant LiHyp1 protein plus adjuvant is protective against tegumentary leishmaniasis.
Jesus MM, Lage DP, Vale DL, Freitas CS, Pimenta BL, Moreira GJL, Ramos FF, Pereira IAG, Bandeira RS, Ludolf F, Tavares GSV, Galdino AS, Duarte MC, Menezes-Souza D, Chávez-Fumagalli MA, Teixeira AL, Gonçalves DU, Roatt BM, Christodoulides M, Martins VT, Coelho EAF. Jesus MM, et al. Among authors: tavares gsv. Parasitol Res. 2023 Dec;122(12):2917-2931. doi: 10.1007/s00436-023-07981-6. Epub 2023 Sep 28. Parasitol Res. 2023. PMID: 37768367
B-Cell Epitopes-Based Chimeric Protein from SARS-CoV-2 N and S Proteins Is Recognized by Specific Antibodies in Serum and Urine Samples from Patients.
Ramos FF, Pereira IAG, Cardoso MM, Bandeira RS, Lage DP, Scussel R, Anastacio RS, Freire VG, Melo MFN, Oliveira-da-Silva JA, Martins VT, Tavares GSV, Vale DL, Freitas CS, Chaves AT, Caporali JFM, Vassallo PF, Ravetti CG, Nobre V, Fonseca FG, Christodoulides M, Machado-de-Ávila RA, Coelho EAF, Ludolf F. Ramos FF, et al. Among authors: tavares gsv. Viruses. 2023 Sep 5;15(9):1877. doi: 10.3390/v15091877. Viruses. 2023. PMID: 37766284 Free PMC article.
The association between rLiHyp1 protein plus adjuvant and amphotericin B is an effective immunotherapy against visceral leishmaniasis in mice.
Lage DP, Martins VT, Vale DL, Freitas CS, Pimenta BL, Moreira GJL, Ramos FF, Pereira IAG, Bandeira RS, de Jesus MM, Ludolf F, Tavares GSV, Chávez-Fumagalli MA, Roatt BM, Christodoulides M, Coelho EAF. Lage DP, et al. Among authors: tavares gsv. Acta Trop. 2023 Oct;246:106986. doi: 10.1016/j.actatropica.2023.106986. Epub 2023 Jul 14. Acta Trop. 2023. PMID: 37453579
Efficacy of an Immunotherapy Combining Immunogenic Chimeric Protein Plus Adjuvant and Amphotericin B against Murine Visceral Leishmaniasis.
Vale DL, Freitas CS, Martins VT, Moreira GJL, Machado AS, Ramos FF, Pereira IAG, Bandeira RS, de Jesus MM, Tavares GSV, Ludolf F, Chávez-Fumagalli MA, Galdino AS, Fujiwara RT, Bueno LL, Roatt BM, Christodoulides M, Coelho EAF, Lage DP. Vale DL, et al. Among authors: tavares gsv. Biology (Basel). 2023 Jun 13;12(6):851. doi: 10.3390/biology12060851. Biology (Basel). 2023. PMID: 37372136 Free PMC article.
In vitro evaluation of antileishmanial activity, mode of action and cellular response induced by vanillin synthetic derivatives against Leishmania species able to cause cutaneous and visceral leishmaniasis.
Freitas CS, Santiago SS, Lage DP, Antinarelli LMR, Oliveira FM, Vale DL, Martins VT, Magalhaes LND, Bandeira RS, Ramos FF, Pereira IAG, de Jesus MM, Ludolf F, Tavares GSV, Costa AV, Ferreira RS, Coimbra ES, Teixeira RR, Coelho EAF. Freitas CS, et al. Among authors: tavares gsv. Exp Parasitol. 2023 Aug;251:108555. doi: 10.1016/j.exppara.2023.108555. Epub 2023 May 27. Exp Parasitol. 2023. PMID: 37247802
Immunotherapy Using Immunogenic Mimotopes Selected by Phage Display plus Amphotericin B Inducing a Therapeutic Response in Mice Infected with Leishmania amazonensis.
Soyer TG, Ramos FF, Pereira IAG, Lage DP, Bandeira RS, de Jesus MM, Costa GP, Machado AS, Freitas CS, Vale DL, Martins VT, Galdino AS, Chávez-Fumagalli MA, Menezes-Souza D, Duarte MC, Roatt BM, Coelho EAF, Tavares GSV. Soyer TG, et al. Among authors: tavares gsv. Pathogens. 2023 Feb 14;12(2):314. doi: 10.3390/pathogens12020314. Pathogens. 2023. PMID: 36839586 Free PMC article.
Exploring drug repositioning for leishmaniasis treatment: Ivermectin plus polymeric micelles induce immunological response and protection against tegumentary leishmaniasis.
Freitas CS, Lage DP, Machado AS, Vale DL, Martins VT, Cardoso JMO, Oliveira-da-Silva JA, Reis TAR, Tavares GSV, Ramos FF, Ludolf F, Pereira IAG, Bandeira RS, Fujiwara RT, Bueno LL, Roatt BM, Chávez-Fumagalli MA, Coelho EAF. Freitas CS, et al. Among authors: tavares gsv. Cytokine. 2023 Apr;164:156143. doi: 10.1016/j.cyto.2023.156143. Epub 2023 Feb 10. Cytokine. 2023. PMID: 36774730
Recombinant endonuclease III protein from Leishmania infantum associated with Th1-type adjuvants is immunogenic and induces protection against visceral leishmaniasis.
Lage DP, Machado AS, Freitas CS, Vale DL, Linhares FP, Cardoso JMO, Oliveira-da-Silva JA, Ramos FF, Pereira IAG, Ludolf F, Tavares GSV, Bandeira RS, Oliveira JS, Menezes-Souza D, Duarte MC, Galdino AS, Christodoulides M, Chávez-Fumagalli MA, Roatt BM, Martins VT, Coelho EAF. Lage DP, et al. Among authors: tavares gsv. Mol Immunol. 2023 Mar;155:79-90. doi: 10.1016/j.molimm.2023.01.011. Epub 2023 Jan 31. Mol Immunol. 2023. PMID: 36731193
57 results