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Transcriptomics in Toxicogenomics, Part I: Experimental Design, Technologies, Publicly Available Data, and Regulatory Aspects.
Kinaret PAS, Serra A, Federico A, Kohonen P, Nymark P, Liampa I, Ha MK, Choi JS, Jagiello K, Sanabria N, Melagraki G, Cattelani L, Fratello M, Sarimveis H, Afantitis A, Yoon TH, Gulumian M, Grafström R, Puzyn T, Greco D. Kinaret PAS, et al. Among authors: grafstrom r. Nanomaterials (Basel). 2020 Apr 15;10(4):750. doi: 10.3390/nano10040750. Nanomaterials (Basel). 2020. PMID: 32326418 Free PMC article. Review.
Cancer biology, toxicology and alternative methods development go hand-in-hand.
Kohonen P, Ceder R, Smit I, Hongisto V, Myatt G, Hardy B, Spjuth O, Grafström R. Kohonen P, et al. Among authors: grafstrom r. Basic Clin Pharmacol Toxicol. 2014 Jul;115(1):50-8. doi: 10.1111/bcpt.12257. Epub 2014 May 23. Basic Clin Pharmacol Toxicol. 2014. PMID: 24779563 Free article. Review.
The eNanoMapper database for nanomaterial safety information.
Jeliazkova N, Chomenidis C, Doganis P, Fadeel B, Grafström R, Hardy B, Hastings J, Hegi M, Jeliazkov V, Kochev N, Kohonen P, Munteanu CR, Sarimveis H, Smeets B, Sopasakis P, Tsiliki G, Vorgrimmler D, Willighagen E. Jeliazkova N, et al. Among authors: grafstrom r. Beilstein J Nanotechnol. 2015 Jul 27;6:1609-34. doi: 10.3762/bjnano.6.165. eCollection 2015. Beilstein J Nanotechnol. 2015. PMID: 26425413 Free PMC article.
Integrated analysis of in vitro data and the adverse outcome pathway framework for prioritization and regulatory applications: An exploratory case study using publicly available data on piperonyl butoxide and liver models.
Oki NO, Farcal L, Abdelaziz A, Florean O, Doktorova TY, Exner T, Kohonen P, Grafström R, Hardy B. Oki NO, et al. Among authors: grafstrom r. Toxicol In Vitro. 2019 Feb;54:23-32. doi: 10.1016/j.tiv.2018.09.002. Epub 2018 Sep 7. Toxicol In Vitro. 2019. PMID: 30196099 Free article.
Toward Rigorous Materials Production: New Approach Methodologies Have Extensive Potential to Improve Current Safety Assessment Practices.
Nymark P, Bakker M, Dekkers S, Franken R, Fransman W, García-Bilbao A, Greco D, Gulumian M, Hadrup N, Halappanavar S, Hongisto V, Hougaard KS, Jensen KA, Kohonen P, Koivisto AJ, Dal Maso M, Oosterwijk T, Poikkimäki M, Rodriguez-Llopis I, Stierum R, Sørli JB, Grafström R. Nymark P, et al. Among authors: grafstrom r. Small. 2020 Feb;16(6):e1904749. doi: 10.1002/smll.201904749. Epub 2020 Jan 8. Small. 2020. PMID: 31913582 Review.
NanoSolveIT Project: Driving nanoinformatics research to develop innovative and integrated tools for in silico nanosafety assessment.
Afantitis A, Melagraki G, Isigonis P, Tsoumanis A, Varsou DD, Valsami-Jones E, Papadiamantis A, Ellis LA, Sarimveis H, Doganis P, Karatzas P, Tsiros P, Liampa I, Lobaskin V, Greco D, Serra A, Kinaret PAS, Saarimäki LA, Grafström R, Kohonen P, Nymark P, Willighagen E, Puzyn T, Rybinska-Fryca A, Lyubartsev A, Alstrup Jensen K, Brandenburg JG, Lofts S, Svendsen C, Harrison S, Maier D, Tamm K, Jänes J, Sikk L, Dusinska M, Longhin E, Rundén-Pran E, Mariussen E, El Yamani N, Unger W, Radnik J, Tropsha A, Cohen Y, Leszczynski J, Ogilvie Hendren C, Wiesner M, Winkler D, Suzuki N, Yoon TH, Choi JS, Sanabria N, Gulumian M, Lynch I. Afantitis A, et al. Among authors: grafstrom r. Comput Struct Biotechnol J. 2020 Mar 7;18:583-602. doi: 10.1016/j.csbj.2020.02.023. eCollection 2020. Comput Struct Biotechnol J. 2020. PMID: 32226594 Free PMC article. Review.
Transcriptomics in Toxicogenomics, Part III: Data Modelling for Risk Assessment.
Serra A, Fratello M, Cattelani L, Liampa I, Melagraki G, Kohonen P, Nymark P, Federico A, Kinaret PAS, Jagiello K, Ha MK, Choi JS, Sanabria N, Gulumian M, Puzyn T, Yoon TH, Sarimveis H, Grafström R, Afantitis A, Greco D. Serra A, et al. Among authors: grafstrom r. Nanomaterials (Basel). 2020 Apr 8;10(4):708. doi: 10.3390/nano10040708. Nanomaterials (Basel). 2020. PMID: 32276469 Free PMC article. Review.
171 results