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Pan-cancer image-based detection of clinically actionable genetic alterations.
Kather JN, Heij LR, Grabsch HI, Loeffler C, Echle A, Muti HS, Krause J, Niehues JM, Sommer KAJ, Bankhead P, Kooreman LFS, Schulte JJ, Cipriani NA, Buelow RD, Boor P, Ortiz-Brüchle NN, Hanby AM, Speirs V, Kochanny S, Patnaik A, Srisuwananukorn A, Brenner H, Hoffmeister M, van den Brandt PA, Jäger D, Trautwein C, Pearson AT, Luedde T. Kather JN, et al. Among authors: grabsch hi. Nat Cancer. 2020 Aug;1(8):789-799. doi: 10.1038/s43018-020-0087-6. Epub 2020 Jul 27. Nat Cancer. 2020. PMID: 33763651 Free PMC article.
Deep learning can predict microsatellite instability directly from histology in gastrointestinal cancer.
Kather JN, Pearson AT, Halama N, Jäger D, Krause J, Loosen SH, Marx A, Boor P, Tacke F, Neumann UP, Grabsch HI, Yoshikawa T, Brenner H, Chang-Claude J, Hoffmeister M, Trautwein C, Luedde T. Kather JN, et al. Among authors: grabsch hi. Nat Med. 2019 Jul;25(7):1054-1056. doi: 10.1038/s41591-019-0462-y. Epub 2019 Jun 3. Nat Med. 2019. PMID: 31160815 Free PMC article.
Clinical-Grade Detection of Microsatellite Instability in Colorectal Tumors by Deep Learning.
Echle A, Grabsch HI, Quirke P, van den Brandt PA, West NP, Hutchins GGA, Heij LR, Tan X, Richman SD, Krause J, Alwers E, Jenniskens J, Offermans K, Gray R, Brenner H, Chang-Claude J, Trautwein C, Pearson AT, Boor P, Luedde T, Gaisa NT, Hoffmeister M, Kather JN. Echle A, et al. Among authors: grabsch hi. Gastroenterology. 2020 Oct;159(4):1406-1416.e11. doi: 10.1053/j.gastro.2020.06.021. Epub 2020 Jun 17. Gastroenterology. 2020. PMID: 32562722 Free PMC article.
Deep learning detects genetic alterations in cancer histology generated by adversarial networks.
Krause J, Grabsch HI, Kloor M, Jendrusch M, Echle A, Buelow RD, Boor P, Luedde T, Brinker TJ, Trautwein C, Pearson AT, Quirke P, Jenniskens J, Offermans K, van den Brandt PA, Kather JN. Krause J, et al. Among authors: grabsch hi. J Pathol. 2021 May;254(1):70-79. doi: 10.1002/path.5638. Epub 2021 Mar 16. J Pathol. 2021. PMID: 33565124 Free article.
Validity and Reproducibility of Immunohistochemical Scoring by Trained Non-Pathologists on Tissue Microarrays.
Jenniskens JCA, Offermans K, Samarska I, Fazzi GE, Simons CCJM, Smits KM, Schouten LJ, Weijenberg MP, van den Brandt PA, Grabsch HI. Jenniskens JCA, et al. Among authors: grabsch hi. Cancer Epidemiol Biomarkers Prev. 2021 Oct;30(10):1867-1874. doi: 10.1158/1055-9965.EPI-21-0295. Epub 2021 Jul 16. Cancer Epidemiol Biomarkers Prev. 2021. PMID: 34272264
Development and validation of deep learning classifiers to detect Epstein-Barr virus and microsatellite instability status in gastric cancer: a retrospective multicentre cohort study.
Muti HS, Heij LR, Keller G, Kohlruss M, Langer R, Dislich B, Cheong JH, Kim YW, Kim H, Kook MC, Cunningham D, Allum WH, Langley RE, Nankivell MG, Quirke P, Hayden JD, West NP, Irvine AJ, Yoshikawa T, Oshima T, Huss R, Grosser B, Roviello F, d'Ignazio A, Quaas A, Alakus H, Tan X, Pearson AT, Luedde T, Ebert MP, Jäger D, Trautwein C, Gaisa NT, Grabsch HI, Kather JN. Muti HS, et al. Among authors: grabsch hi. Lancet Digit Health. 2021 Oct;3(10):e654-e664. doi: 10.1016/S2589-7500(21)00133-3. Epub 2021 Aug 17. Lancet Digit Health. 2021. PMID: 34417147 Free PMC article.
Weakly supervised annotation-free cancer detection and prediction of genotype in routine histopathology.
Schrammen PL, Ghaffari Laleh N, Echle A, Truhn D, Schulz V, Brinker TJ, Brenner H, Chang-Claude J, Alwers E, Brobeil A, Kloor M, Heij LR, Jäger D, Trautwein C, Grabsch HI, Quirke P, West NP, Hoffmeister M, Kather JN. Schrammen PL, et al. Among authors: grabsch hi. J Pathol. 2022 Jan;256(1):50-60. doi: 10.1002/path.5800. Epub 2021 Oct 22. J Pathol. 2022. PMID: 34561876 Free article.
Deep learning identifies inflamed fat as a risk factor for lymph node metastasis in early colorectal cancer.
Brockmoeller S, Echle A, Ghaffari Laleh N, Eiholm S, Malmstrøm ML, Plato Kuhlmann T, Levic K, Grabsch HI, West NP, Saldanha OL, Kouvidi K, Bono A, Heij LR, Brinker TJ, Gögenür I, Quirke P, Kather JN. Brockmoeller S, et al. Among authors: grabsch hi. J Pathol. 2022 Mar;256(3):269-281. doi: 10.1002/path.5831. Epub 2021 Dec 28. J Pathol. 2022. PMID: 34738636
196 results