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Structure-Activity Relationship Studies of Acetazolamide-Based Carbonic Anhydrase Inhibitors with Activity against Neisseria gonorrhoeae.
ACS Infect Dis. 2021 Jul 9;7(7):1969-1984. doi: 10.1021/acsinfecdis.1c00055. Epub 2021 Mar 25.
ACS Infect Dis. 2021.
PMID: 33765392
Free PMC article.
Optimization of Acetazolamide-Based Scaffold as Potent Inhibitors of Vancomycin-Resistant Enterococcus.
Kaur J, Cao X, Abutaleb NS, Elkashif A, Graboski AL, Krabill AD, AbdelKhalek AH, An W, Bhardwaj A, Seleem MN, Flaherty DP.
Kaur J, et al. Among authors: graboski al.
J Med Chem. 2020 Sep 10;63(17):9540-9562. doi: 10.1021/acs.jmedchem.0c00734. Epub 2020 Aug 11.
J Med Chem. 2020.
PMID: 32787141
Free PMC article.
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Metagenomics combined with activity-based proteomics point to gut bacterial enzymes that reactivate mycophenolate.
Simpson JB, Sekela JJ, Graboski AL, Borlandelli VB, Bivins MM, Barker NK, Sorgen AA, Mordant AL, Johnson RL, Bhatt AP, Fodor AA, Herring LE, Overkleeft H, Lee JR, Redinbo MR.
Simpson JB, et al. Among authors: graboski al.
Gut Microbes. 2022 Jan-Dec;14(1):2107289. doi: 10.1080/19490976.2022.2107289.
Gut Microbes. 2022.
PMID: 35953888
Free PMC article.
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Gut-Derived Protein-Bound Uremic Toxins.
Graboski AL, Redinbo MR.
Graboski AL, et al.
Toxins (Basel). 2020 Sep 11;12(9):590. doi: 10.3390/toxins12090590.
Toxins (Basel). 2020.
PMID: 32932981
Free PMC article.
Review.
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Mechanism-based inhibition of gut microbial tryptophanases reduces serum indoxyl sulfate.
Graboski AL, Kowalewski ME, Simpson JB, Cao X, Ha M, Zhang J, Walton WG, Flaherty DP, Redinbo MR.
Graboski AL, et al.
Cell Chem Biol. 2023 Nov 16;30(11):1402-1413.e7. doi: 10.1016/j.chembiol.2023.07.015. Epub 2023 Aug 25.
Cell Chem Biol. 2023.
PMID: 37633277
Free article.
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