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The dopamine receptor D1 inhibitor, SKF83566, suppresses GBM stemness and invasion through the DRD1-c-Myc-UHRF1 interactions.
Xue Z, Zhang Y, Zhao R, Liu X, Grützmann K, Klink B, Zhang X, Wang S, Zhao W, Sun Y, Han M, Wang X, Hu Y, Liu X, Yang N, Qiu C, Li W, Huang B, Li X, Bjerkvig R, Wang J, Zhou W. Xue Z, et al. Among authors: grutzmann k. J Exp Clin Cancer Res. 2024 Jan 22;43(1):25. doi: 10.1186/s13046-024-02947-7. J Exp Clin Cancer Res. 2024. PMID: 38246990 Free PMC article.
Targeted capture-based NGS is superior to multiplex PCR-based NGS for hereditary BRCA1 and BRCA2 gene analysis in FFPE tumor samples.
Zakrzewski F, Gieldon L, Rump A, Seifert M, Grützmann K, Krüger A, Loos S, Zeugner S, Hackmann K, Porrmann J, Wagner J, Kast K, Wimberger P, Baretton G, Schröck E, Aust D, Klink B. Zakrzewski F, et al. Among authors: grutzmann k. BMC Cancer. 2019 Apr 27;19(1):396. doi: 10.1186/s12885-019-5584-6. BMC Cancer. 2019. PMID: 31029168 Free PMC article.
Patient-Derived Organoids of Cholangiocarcinoma.
Maier CF, Zhu L, Nanduri LK, Kühn D, Kochall S, Thepkaysone ML, William D, Grützmann K, Klink B, Betge J, Weitz J, Rahbari NN, Reißfelder C, Schölch S. Maier CF, et al. Among authors: grutzmann k. Int J Mol Sci. 2021 Aug 12;22(16):8675. doi: 10.3390/ijms22168675. Int J Mol Sci. 2021. PMID: 34445380 Free PMC article.
Lactate dehydrogenases promote glioblastoma growth and invasion via a metabolic symbiosis.
Guyon J, Fernandez-Moncada I, Larrieu CM, Bouchez CL, Pagano Zottola AC, Galvis J, Chouleur T, Burban A, Joseph K, Ravi VM, Espedal H, Røsland GV, Daher B, Barre A, Dartigues B, Karkar S, Rudewicz J, Romero-Garmendia I, Klink B, Grützmann K, Derieppe MA, Molinié T, Obad N, Léon C, Seano G, Miletic H, Heiland DH, Marsicano G, Nikolski M, Bjerkvig R, Bikfalvi A, Daubon T. Guyon J, et al. Among authors: grutzmann k. EMBO Mol Med. 2022 Dec 7;14(12):e15343. doi: 10.15252/emmm.202115343. Epub 2022 Oct 24. EMBO Mol Med. 2022. PMID: 36278433 Free PMC article.
Identification of Epigenetically Regulated Genes Distinguishing Intracranial from Extracranial Melanoma Metastases.
Westphal D, Meinhardt M, Grützmann K, Schöne L, Steininger J, Neuhaus LT, Wiegel M, Schrimpf D, Aust DE, Schröck E, Baretton GB, Beissert S, Juratli TA, Schackert GG, Gravemeyer J, Becker JC, von Deimling A, Koelsche C, Klink B, Meier F, Schulz A, Muders MH, Seifert M. Westphal D, et al. Among authors: grutzmann k. J Invest Dermatol. 2023 Jul;143(7):1233-1245.e17. doi: 10.1016/j.jid.2023.01.011. Epub 2023 Jan 28. J Invest Dermatol. 2023. PMID: 36716920 Free article.
Human gastric cancer modelling using organoids.
Seidlitz T, Merker SR, Rothe A, Zakrzewski F, von Neubeck C, Grützmann K, Sommer U, Schweitzer C, Schölch S, Uhlemann H, Gaebler AM, Werner K, Krause M, Baretton GB, Welsch T, Koo BK, Aust DE, Klink B, Weitz J, Stange DE. Seidlitz T, et al. Among authors: grutzmann k. Gut. 2019 Feb;68(2):207-217. doi: 10.1136/gutjnl-2017-314549. Epub 2018 Apr 27. Gut. 2019. PMID: 29703791 Free PMC article.
Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia.
Latham SL, Ehmke N, Reinke PYA, Taft MH, Eicke D, Reindl T, Stenzel W, Lyons MJ, Friez MJ, Lee JA, Hecker R, Frühwald MC, Becker K, Neuhann TM, Horn D, Schrock E, Niehaus I, Sarnow K, Grützmann K, Gawehn L, Klink B, Rump A, Chaponnier C, Figueiredo C, Knöfler R, Manstein DJ, Di Donato N. Latham SL, et al. Among authors: grutzmann k. Nat Commun. 2018 Oct 12;9(1):4250. doi: 10.1038/s41467-018-06713-0. Nat Commun. 2018. PMID: 30315159 Free PMC article.
Author Correction: Variants in exons 5 and 6 of ACTB cause syndromic thrombocytopenia.
Latham SL, Ehmke N, Reinke PYA, Taft MH, Eicke D, Reindl T, Stenzel W, Lyons MJ, Friez MJ, Lee JA, Hecker R, Frühwald MC, Becker K, Neuhann TM, Horn D, Schrock E, Niehaus I, Sarnow K, Grützmann K, Gawehn L, Klink B, Rump A, Chaponnier C, Figueiredo C, Knöfler R, Manstein DJ, Di Donato N. Latham SL, et al. Among authors: grutzmann k. Nat Commun. 2018 Nov 19;9(1):4930. doi: 10.1038/s41467-018-07404-6. Nat Commun. 2018. PMID: 30451859 Free PMC article.
43 results