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Intestinal Microbiota Reduction Followed by Fasting Discloses Microbial Triggering of Inflammation in Rheumatoid Arthritis.
Häupl T, Sörensen T, Smiljanovic B, Darcy M, Scheder-Bieschin J, Steckhan N, Hartmann AM, Koppold DA, Stuhlmüller B, Skriner K, Walewska BM, Hoppe B, Bonin M, Burmester GR, Schendel P, Feist E, Liere K, Meixner M, Kessler C, Grützkau A, Michalsen A. Häupl T, et al. Among authors: grutzkau a. J Clin Med. 2023 Jun 28;12(13):4359. doi: 10.3390/jcm12134359. J Clin Med. 2023. PMID: 37445394 Free PMC article.
Monocyte alterations in rheumatoid arthritis are dominated by preterm release from bone marrow and prominent triggering in the joint.
Smiljanovic B, Radzikowska A, Kuca-Warnawin E, Kurowska W, Grün JR, Stuhlmüller B, Bonin M, Schulte-Wrede U, Sörensen T, Kyogoku C, Bruns A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Burmester GR, Radbruch A, Grützkau A, Maslinski W, Häupl T. Smiljanovic B, et al. Among authors: grutzkau a. Ann Rheum Dis. 2018 Feb;77(2):300-308. doi: 10.1136/annrheumdis-2017-211649. Epub 2017 Nov 30. Ann Rheum Dis. 2018. PMID: 29191820 Free PMC article.
Synovial tissue transcriptomes of long-standing rheumatoid arthritis are dominated by activated macrophages that reflect microbial stimulation.
Smiljanovic B, Grützkau A, Sörensen T, Grün JR, Vogl T, Bonin M, Schendel P, Stuhlmüller B, Claussnitzer A, Hermann S, Ohrndorf S, Aupperle K, Backhaus M, Radbruch A, Burmester GR, Häupl T. Smiljanovic B, et al. Among authors: grutzkau a. Sci Rep. 2020 May 13;10(1):7907. doi: 10.1038/s41598-020-64431-4. Sci Rep. 2020. PMID: 32404914 Free PMC article.
Peripheral blood mononuclear cells are hypomethylated in active rheumatoid arthritis and methylation correlates with disease activity.
Liebold I, Grützkau A, Göckeritz A, Gerl V, Lindquist R, Feist E, Zänker M, Häupl T, Poddubnyy D, Zernicke J, Smiljanovic B, Alexander T, Burmester GR, Gay S, Stuhlmüller B. Liebold I, et al. Among authors: grutzkau a. Rheumatology (Oxford). 2021 Apr 6;60(4):1984-1995. doi: 10.1093/rheumatology/keaa649. Rheumatology (Oxford). 2021. PMID: 33200208
The multifaceted balance of TNF-α and type I/II interferon responses in SLE and RA: how monocytes manage the impact of cytokines.
Smiljanovic B, Grün JR, Biesen R, Schulte-Wrede U, Baumgrass R, Stuhlmüller B, Maslinski W, Hiepe F, Burmester GR, Radbruch A, Häupl T, Grützkau A. Smiljanovic B, et al. Among authors: grutzkau a. J Mol Med (Berl). 2012 Nov;90(11):1295-309. doi: 10.1007/s00109-012-0907-y. Epub 2012 May 19. J Mol Med (Berl). 2012. PMID: 22610275
Upregulation of immunoproteasome subunits in myositis indicates active inflammation with involvement of antigen presenting cells, CD8 T-cells and IFNΓ.
Ghannam K, Martinez-Gamboa L, Spengler L, Krause S, Smiljanovic B, Bonin M, Bhattarai S, Grützkau A, Burmester GR, Häupl T, Feist E. Ghannam K, et al. Among authors: grutzkau a. PLoS One. 2014 Aug 6;9(8):e104048. doi: 10.1371/journal.pone.0104048. eCollection 2014. PLoS One. 2014. PMID: 25098831 Free PMC article. Clinical Trial.
100 results