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Ageing-associated changes in transcriptional elongation influence longevity.
Debès C, Papadakis A, Grönke S, Karalay Ö, Tain LS, Mizi A, Nakamura S, Hahn O, Weigelt C, Josipovic N, Zirkel A, Brusius I, Sofiadis K, Lamprousi M, Lu YX, Huang W, Esmaillie R, Kubacki T, Späth MR, Schermer B, Benzing T, Müller RU, Antebi A, Partridge L, Papantonis A, Beyer A. Debès C, et al. Among authors: gronke s. Nature. 2023 Apr;616(7958):814-821. doi: 10.1038/s41586-023-05922-y. Epub 2023 Apr 12. Nature. 2023. PMID: 37046086 Free PMC article.
A Drosophila Model of Neuronopathic Gaucher Disease Demonstrates Lysosomal-Autophagic Defects and Altered mTOR Signalling and Is Functionally Rescued by Rapamycin.
Kinghorn KJ, Grönke S, Castillo-Quan JI, Woodling NS, Li L, Sirka E, Gegg M, Mills K, Hardy J, Bjedov I, Partridge L. Kinghorn KJ, et al. Among authors: gronke s. J Neurosci. 2016 Nov 16;36(46):11654-11670. doi: 10.1523/JNEUROSCI.4527-15.2016. J Neurosci. 2016. PMID: 27852774 Free PMC article.
Sense and antisense RNA are not toxic in Drosophila models of C9orf72-associated ALS/FTD.
Moens TG, Mizielinska S, Niccoli T, Mitchell JS, Thoeng A, Ridler CE, Grönke S, Esser J, Heslegrave A, Zetterberg H, Partridge L, Isaacs AM. Moens TG, et al. Among authors: gronke s. Acta Neuropathol. 2018 Mar;135(3):445-457. doi: 10.1007/s00401-017-1798-3. Epub 2018 Jan 29. Acta Neuropathol. 2018. PMID: 29380049 Free PMC article.
Mutations of mitochondrial DNA are not major contributors to aging of fruit flies.
Kauppila TES, Bratic A, Jensen MB, Baggio F, Partridge L, Jasper H, Grönke S, Larsson NG. Kauppila TES, et al. Among authors: gronke s. Proc Natl Acad Sci U S A. 2018 Oct 9;115(41):E9620-E9629. doi: 10.1073/pnas.1721683115. Epub 2018 Sep 24. Proc Natl Acad Sci U S A. 2018. PMID: 30249665 Free PMC article.
Loss of miR-210 leads to progressive retinal degeneration in Drosophila melanogaster.
Weigelt CM, Hahn O, Arlt K, Gruhn M, Jahn AJ, Eßer J, Werner JA, Klein C, Büschges A, Grönke S, Partridge L. Weigelt CM, et al. Among authors: gronke s. Life Sci Alliance. 2019 Jan 22;2(1):e201800149. doi: 10.26508/lsa.201800149. Print 2019 Feb. Life Sci Alliance. 2019. PMID: 30670478 Free PMC article.
65 results