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DICAM promotes TH17 lymphocyte trafficking across the blood-brain barrier during autoimmune neuroinflammation.
Charabati M, Grasmuck C, Ghannam S, Bourbonnière L, Fournier AP, Lécuyer MA, Tastet O, Kebir H, Rébillard RM, Hoornaert C, Gowing E, Larouche S, Fortin O, Pittet C, Filali-Mouhim A, Lahav B, Moumdjian R, Bouthillier A, Girard M, Duquette P, Cayrol R, Peelen E, Quintana FJ, Antel JP, Flügel A, Larochelle C, Arbour N, Zandee S, Prat A. Charabati M, et al. Among authors: gowing e. Sci Transl Med. 2022 Jan 5;14(626):eabj0473. doi: 10.1126/scitranslmed.abj0473. Epub 2022 Jan 5. Sci Transl Med. 2022. PMID: 34985970
Dual role of ALCAM in neuroinflammation and blood-brain barrier homeostasis.
Lécuyer MA, Saint-Laurent O, Bourbonnière L, Larouche S, Larochelle C, Michel L, Charabati M, Abadier M, Zandee S, Haghayegh Jahromi N, Gowing E, Pittet C, Lyck R, Engelhardt B, Prat A. Lécuyer MA, et al. Among authors: gowing e. Proc Natl Acad Sci U S A. 2017 Jan 24;114(4):E524-E533. doi: 10.1073/pnas.1614336114. Epub 2017 Jan 9. Proc Natl Acad Sci U S A. 2017. PMID: 28069965 Free PMC article.
Interleukin-26, preferentially produced by TH17 lymphocytes, regulates CNS barrier function.
Broux B, Zandee S, Gowing E, Charabati M, Lécuyer MA, Tastet O, Hachehouche L, Bourbonnière L, Ouimet JP, Lemaitre F, Larouche S, Cayrol R, Bouthillier A, Moumdjian R, Lahav B, Poirier J, Duquette P, Arbour N, Peelen E, Prat A. Broux B, et al. Among authors: gowing e. Neurol Neuroimmunol Neuroinflamm. 2020 Aug 11;7(6):e870. doi: 10.1212/NXI.0000000000000870. Print 2020 Nov. Neurol Neuroimmunol Neuroinflamm. 2020. PMID: 32788322 Free PMC article.
Oncostatin M triggers brain inflammation by compromising blood-brain barrier integrity.
Hermans D, Houben E, Baeten P, Slaets H, Janssens K, Hoeks C, Hosseinkhani B, Duran G, Bormans S, Gowing E, Hoornaert C, Beckers L, Fung WK, Schroten H, Ishikawa H, Fraussen J, Thoelen R, de Vries HE, Kooij G, Zandee S, Prat A, Hellings N, Broux B. Hermans D, et al. Among authors: gowing e. Acta Neuropathol. 2022 Aug;144(2):259-281. doi: 10.1007/s00401-022-02445-0. Epub 2022 Jun 6. Acta Neuropathol. 2022. PMID: 35666306
EGFL7 reduces CNS inflammation in mouse.
Larochelle C, Uphaus T, Broux B, Gowing E, Paterka M, Michel L, Dudvarski Stankovic N, Bicker F, Lemaître F, Prat A, Schmidt MHH, Zipp F. Larochelle C, et al. Among authors: gowing e. Nat Commun. 2018 Feb 26;9(1):819. doi: 10.1038/s41467-018-03186-z. Nat Commun. 2018. PMID: 29483510 Free PMC article.
Inflammation-induced endothelial to mesenchymal transition promotes brain endothelial cell dysfunction and occurs during multiple sclerosis pathophysiology.
Derada Troletti C, Fontijn RD, Gowing E, Charabati M, van Het Hof B, Didouh I, van der Pol SMA, Geerts D, Prat A, van Horssen J, Kooij G, de Vries HE. Derada Troletti C, et al. Among authors: gowing e. Cell Death Dis. 2019 Jan 18;10(2):45. doi: 10.1038/s41419-018-1294-2. Cell Death Dis. 2019. PMID: 30718504 Free PMC article.
Identification of SARS-CoV-2-specific immune alterations in acutely ill patients.
Rébillard RM, Charabati M, Grasmuck C, Filali-Mouhim A, Tastet O, Brassard N, Daigneault A, Bourbonnière L, Anand SP, Balthazard R, Beaudoin-Bussières G, Gasser R, Benlarbi M, Moratalla AC, Solorio YC, Boutin M, Farzam-Kia N, Descôteaux-Dinelle J, Fournier AP, Gowing E, Laumaea A, Jamann H, Lahav B, Goyette G, Lemaître F, Mamane VH, Prévost J, Richard J, Thai K, Cailhier JF, Chomont N, Finzi A, Chassé M, Durand M, Arbour N, Kaufmann DE, Prat A, Larochelle C. Rébillard RM, et al. Among authors: gowing e. J Clin Invest. 2021 Apr 15;131(8):e145853. doi: 10.1172/JCI145853. J Clin Invest. 2021. PMID: 33635833 Free PMC article.
Notch signaling is impaired during inflammation in a Lunatic Fringe-dependent manner.
Derada Troletti C, Lopes Pinheiro MA, Charabati M, Gowing E, van Het Hof B, van der Pol SMA, Geerts D, Prat A, Fontijn RD, Unger WW, de Vries HE. Derada Troletti C, et al. Among authors: gowing e. Brain Behav Immun. 2018 Mar;69:48-56. doi: 10.1016/j.bbi.2017.12.016. Epub 2017 Dec 28. Brain Behav Immun. 2018. PMID: 29289661
36 results