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Page 1
Safety pharmacology--current and emerging concepts.
Hamdam J, Sethu S, Smith T, Alfirevic A, Alhaidari M, Atkinson J, Ayala M, Box H, Cross M, Delaunois A, Dermody A, Govindappa K, Guillon JM, Jenkins R, Kenna G, Lemmer B, Meecham K, Olayanju A, Pestel S, Rothfuss A, Sidaway J, Sison-Young R, Smith E, Stebbings R, Tingle Y, Valentin JP, Williams A, Williams D, Park K, Goldring C. Hamdam J, et al. Among authors: govindappa k. Toxicol Appl Pharmacol. 2013 Dec 1;273(2):229-41. doi: 10.1016/j.taap.2013.04.039. Epub 2013 Jun 1. Toxicol Appl Pharmacol. 2013. PMID: 23732082 Review.
Immunogenicity to biologics: mechanisms, prediction and reduction.
Sethu S, Govindappa K, Alhaidari M, Pirmohamed M, Park K, Sathish J. Sethu S, et al. Among authors: govindappa k. Arch Immunol Ther Exp (Warsz). 2012 Oct;60(5):331-44. doi: 10.1007/s00005-012-0189-7. Epub 2012 Aug 29. Arch Immunol Ther Exp (Warsz). 2012. PMID: 22930363 Free article. Review.
Immunoglobulin G1 and immunoglobulin G4 antibodies in multiple sclerosis patients treated with IFNβ interact with the endogenous cytokine and activate complement.
Sethu S, Govindappa K, Quinn P, Wadhwa M, Stebbings R, Boggild M, Naisbitt D, Kimber I, Pirmohamed M, Park K, Sathish J. Sethu S, et al. Among authors: govindappa k. Clin Immunol. 2013 Aug;148(2):177-85. doi: 10.1016/j.clim.2013.05.008. Epub 2013 May 22. Clin Immunol. 2013. PMID: 23770627 Free PMC article.
Challenges and approaches for the development of safer immunomodulatory biologics.
Sathish JG, Sethu S, Bielsky MC, de Haan L, French NS, Govindappa K, Green J, Griffiths CE, Holgate S, Jones D, Kimber I, Moggs J, Naisbitt DJ, Pirmohamed M, Reichmann G, Sims J, Subramanyam M, Todd MD, Van Der Laan JW, Weaver RJ, Park BK. Sathish JG, et al. Among authors: govindappa k. Nat Rev Drug Discov. 2013 Apr;12(4):306-24. doi: 10.1038/nrd3974. Nat Rev Drug Discov. 2013. PMID: 23535934 Free PMC article. Review.
Effect of Smart Dentin Replacement, Biodentine, and Its Combination for Dentin Replacement as Alternatives to Full-crown Coverage for Endodontically Treated Molars: An In Vitro Study.
Magaravalli SR, Patel SJ, Rangaswamy P, Ramachandra S, Govindappa K, Hiremath V. Magaravalli SR, et al. Among authors: govindappa k. J Int Soc Prev Community Dent. 2019 Nov 12;9(6):559-565. doi: 10.4103/jispcd.JISPCD_336_19. eCollection 2019 Nov-Dec. J Int Soc Prev Community Dent. 2019. PMID: 32039075 Free PMC article.
Efficacy of Low-Dose Buspirone for Restricted and Repetitive Behavior in Young Children with Autism Spectrum Disorder: A Randomized Trial.
Chugani DC, Chugani HT, Wiznitzer M, Parikh S, Evans PA, Hansen RL, Nass R, Janisse JJ, Dixon-Thomas P, Behen M, Rothermel R, Parker JS, Kumar A, Muzik O, Edwards DJ, Hirtz D; Autism Center of Excellence Network. Chugani DC, et al. J Pediatr. 2016 Mar;170:45-53.e1-4. doi: 10.1016/j.jpeds.2015.11.033. Epub 2015 Dec 30. J Pediatr. 2016. PMID: 26746121 Free article. Clinical Trial.