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FRET-Based Screening Identifies p38 MAPK and PKC Inhibition as Targets for Prevention of Seeded α-Synuclein Aggregation.
Svanbergsson A, Ek F, Martinsson I, Rodo J, Liu D, Brandi E, Haikal C, Torres-Garcia L, Li W, Gouras G, Olsson R, Björklund T, Li JY. Svanbergsson A, et al. Among authors: gouras g. Neurotherapeutics. 2021 Jul;18(3):1692-1709. doi: 10.1007/s13311-021-01070-1. Epub 2021 Jul 13. Neurotherapeutics. 2021. PMID: 34258749 Free PMC article.
Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties.
Azevedo C, Teku G, Pomeshchik Y, Reyes JF, Chumarina M, Russ K, Savchenko E, Hammarberg A, Lamas NJ, Collin A, Gouras GK, Klementieva O, Hallbeck M, Taipa R, Vihinen M, Roybon L. Azevedo C, et al. Among authors: gouras gk. Proc Natl Acad Sci U S A. 2022 Mar 22;119(12):e2111405119. doi: 10.1073/pnas.2111405119. Epub 2022 Mar 16. Proc Natl Acad Sci U S A. 2022. PMID: 35294277 Free PMC article.
Early-life stress elicits peripheral and brain immune activation differently in wild type and 5xFAD mice in a sex-specific manner.
Bachiller S, Hidalgo I, Garcia MG, Boza-Serrano A, Paulus A, Denis Q, Haikal C, Manouchehrian O, Klementieva O, Li JY, Pronk CJ, Gouras GK, Deierborg T. Bachiller S, et al. Among authors: gouras gk. J Neuroinflammation. 2022 Jun 15;19(1):151. doi: 10.1186/s12974-022-02515-w. J Neuroinflammation. 2022. PMID: 35705972 Free PMC article.
Aβ/Amyloid Precursor Protein-Induced Hyperexcitability and Dysregulation of Homeostatic Synaptic Plasticity in Neuron Models of Alzheimer's Disease.
Martinsson I, Quintino L, Garcia MG, Konings SC, Torres-Garcia L, Svanbergsson A, Stange O, England R, Deierborg T, Li JY, Lundberg C, Gouras GK. Martinsson I, et al. Among authors: gouras gk. Front Aging Neurosci. 2022 Jul 6;14:946297. doi: 10.3389/fnagi.2022.946297. eCollection 2022. Front Aging Neurosci. 2022. PMID: 35928998 Free PMC article.
APOE in the bullseye of neurodegenerative diseases: impact of the APOE genotype in Alzheimer's disease pathology and brain diseases.
Fernández-Calle R, Konings SC, Frontiñán-Rubio J, García-Revilla J, Camprubí-Ferrer L, Svensson M, Martinson I, Boza-Serrano A, Venero JL, Nielsen HM, Gouras GK, Deierborg T. Fernández-Calle R, et al. Among authors: gouras gk. Mol Neurodegener. 2022 Sep 24;17(1):62. doi: 10.1186/s13024-022-00566-4. Mol Neurodegener. 2022. PMID: 36153580 Free PMC article. Review.
111 results