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The significant role of mast cells in cancer.
Khazaie K, Blatner NR, Khan MW, Gounari F, Gounaris E, Dennis K, Bonertz A, Tsai FN, Strouch MJ, Cheon E, Phillips JD, Beckhove P, Bentrem DJ. Khazaie K, et al. Among authors: gounaris e. Cancer Metastasis Rev. 2011 Mar;30(1):45-60. doi: 10.1007/s10555-011-9286-z. Cancer Metastasis Rev. 2011. PMID: 21287360 Review.
PI3K/AKT signaling is essential for communication between tissue-infiltrating mast cells, macrophages, and epithelial cells in colitis-induced cancer.
Khan MW, Keshavarzian A, Gounaris E, Melson JE, Cheon EC, Blatner NR, Chen ZE, Tsai FN, Lee G, Ryu H, Barrett TA, Bentrem DJ, Beckhove P, Khazaie K. Khan MW, et al. Among authors: gounaris e. Clin Cancer Res. 2013 May 1;19(9):2342-54. doi: 10.1158/1078-0432.CCR-12-2623. Epub 2013 Mar 13. Clin Cancer Res. 2013. PMID: 23487439 Free PMC article.
Mast cell 5-lipoxygenase activity promotes intestinal polyposis in APCDelta468 mice.
Cheon EC, Khazaie K, Khan MW, Strouch MJ, Krantz SB, Phillips J, Blatner NR, Hix LM, Zhang M, Dennis KL, Salabat MR, Heiferman M, Grippo PJ, Munshi HG, Gounaris E, Bentrem DJ. Cheon EC, et al. Among authors: gounaris e. Cancer Res. 2011 Mar 1;71(5):1627-36. doi: 10.1158/0008-5472.CAN-10-1923. Epub 2011 Jan 7. Cancer Res. 2011. PMID: 21216893
Mast cells are an essential hematopoietic component for polyp development.
Gounaris E, Erdman SE, Restaino C, Gurish MF, Friend DS, Gounari F, Lee DM, Zhang G, Glickman JN, Shin K, Rao VP, Poutahidis T, Weissleder R, McNagny KM, Khazaie K. Gounaris E, et al. Proc Natl Acad Sci U S A. 2007 Dec 11;104(50):19977-82. doi: 10.1073/pnas.0704620104. Epub 2007 Dec 6. Proc Natl Acad Sci U S A. 2007. PMID: 18077429 Free PMC article.
Ablation of 5-lipoxygenase mitigates pancreatic lesion development.
Knab LM, Schultz M, Principe DR, Mascarinas WE, Gounaris E, Munshi HG, Grippo PJ, Bentrem DJ. Knab LM, et al. Among authors: gounaris e. J Surg Res. 2015 Apr;194(2):481-487. doi: 10.1016/j.jss.2014.10.021. Epub 2014 Oct 22. J Surg Res. 2015. PMID: 25454978 Free PMC article.
28 results