Gottschalk S - Search Results

1

Modular chimeric cytokine receptors with leucine zippers enhance the antitumour activity of CAR T cells via JAK/STAT signalling.

Bell M, Lange S, Sejdiu BI, Ibanez J, Shi H, Sun X, Meng X, Nguyen P, Sutton M, Wagner J, Kc A, Langfitt D, Patil SL, Tan H, Pandey RV, Li Y, Yuan ZF, Anido AA, Ho M, Sheppard H, Vogel P, Yu J, Peng J, Chi H, Babu MM, Krenciute G, Gottschalk S. Bell M, et al. Among authors: gottschalk s. Nat Biomed Eng. 2024 Apr;8(4):380-396. doi: 10.1038/s41551-023-01143-w. Epub 2023 Nov 30. Nat Biomed Eng. 2024. PMID: 38036617

2

Characterization and Functional Analysis of scFv-based Chimeric Antigen Receptors to Redirect T Cells to IL13Rα2-positive Glioma.

Krenciute G, Krebs S, Torres D, Wu MF, Liu H, Dotti G, Li XN, Lesniak MS, Balyasnikova IV, Gottschalk S. Krenciute G, et al. Among authors: gottschalk s. Mol Ther. 2016 Feb;24(2):354-363. doi: 10.1038/mt.2015.199. Epub 2015 Oct 30. Mol Ther. 2016. PMID: 26514825 Free PMC article.

3

Transgenic Expression of IL15 Improves Antiglioma Activity of IL13Rα2-CAR T Cells but Results in Antigen Loss Variants.

Krenciute G, Prinzing BL, Yi Z, Wu MF, Liu H, Dotti G, Balyasnikova IV, Gottschalk S. Krenciute G, et al. Among authors: gottschalk s. Cancer Immunol Res. 2017 Jul;5(7):571-581. doi: 10.1158/2326-6066.CIR-16-0376. Epub 2017 May 26. Cancer Immunol Res. 2017. PMID: 28550091 Free PMC article.

4

Inducible Activation of MyD88 and CD40 in CAR T Cells Results in Controllable and Potent Antitumor Activity in Preclinical Solid Tumor Models.

Mata M, Gerken C, Nguyen P, Krenciute G, Spencer DM, Gottschalk S. Mata M, et al. Among authors: gottschalk s. Cancer Discov. 2017 Nov;7(11):1306-1319. doi: 10.1158/2159-8290.CD-17-0263. Epub 2017 Aug 11. Cancer Discov. 2017. PMID: 28801306 Free PMC article.

5

CD28 and 41BB Costimulation Enhances the Effector Function of CD19-Specific Engager T Cells.

Velasquez MP, Szoor A, Vaidya A, Thakkar A, Nguyen P, Wu MF, Liu H, Gottschalk S. Velasquez MP, et al. Among authors: gottschalk s. Cancer Immunol Res. 2017 Oct;5(10):860-870. doi: 10.1158/2326-6066.CIR-17-0171. Epub 2017 Aug 18. Cancer Immunol Res. 2017. PMID: 28821531 Free PMC article.

6

Adoptive Transfer of IL13Rα2-Specific Chimeric Antigen Receptor T Cells Creates a Pro-inflammatory Environment in Glioblastoma.

Pituch KC, Miska J, Krenciute G, Panek WK, Li G, Rodriguez-Cruz T, Wu M, Han Y, Lesniak MS, Gottschalk S, Balyasnikova IV. Pituch KC, et al. Among authors: gottschalk s. Mol Ther. 2018 Apr 4;26(4):986-995. doi: 10.1016/j.ymthe.2018.02.001. Epub 2018 Feb 8. Mol Ther. 2018. PMID: 29503195 Free PMC article.

7

CAR T-cell therapy for glioblastoma: ready for the next round of clinical testing?

Prinzing BL, Gottschalk SM, Krenciute G. Prinzing BL, et al. Expert Rev Anticancer Ther. 2018 May;18(5):451-461. doi: 10.1080/14737140.2018.1451749. Epub 2018 Mar 16. Expert Rev Anticancer Ther. 2018. PMID: 29533108 Free PMC article. Review.

8

Optimizing EphA2-CAR T Cells for the Adoptive Immunotherapy of Glioma.

Yi Z, Prinzing BL, Cao F, Gottschalk S, Krenciute G. Yi Z, et al. Among authors: gottschalk s. Mol Ther Methods Clin Dev. 2018 Feb 2;9:70-80. doi: 10.1016/j.omtm.2018.01.009. eCollection 2018 Jun 15. Mol Ther Methods Clin Dev. 2018. PMID: 29552579 Free PMC article.

9

The Landscape of CAR T Cells Beyond Acute Lymphoblastic Leukemia for Pediatric Solid Tumors.

DeRenzo C, Krenciute G, Gottschalk S. DeRenzo C, et al. Among authors: gottschalk s. Am Soc Clin Oncol Educ Book. 2018 May 23;38:830-837. doi: 10.1200/EDBK_200773. Am Soc Clin Oncol Educ Book. 2018. PMID: 30231350 Free article. Review.

10

Route of 41BB/41BBL Costimulation Determines Effector Function of B7-H3-CAR.CD28ζ T Cells.

Nguyen P, Okeke E, Clay M, Haydar D, Justice J, O'Reilly C, Pruett-Miller S, Papizan J, Moore J, Zhou S, Throm R, Krenciute G, Gottschalk S, DeRenzo C. Nguyen P, et al. Among authors: gottschalk s. Mol Ther Oncolytics. 2020 Jun 23;18:202-214. doi: 10.1016/j.omto.2020.06.018. eCollection 2020 Sep 25. Mol Ther Oncolytics. 2020. PMID: 32728609 Free PMC article.

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