Gottschalk R - Search Results

1

Keratinocyte gene expression profiles discriminate sensitizing and irritating compounds.

Vandebriel RJ, Pennings JL, Baken KA, Pronk TE, Boorsma A, Gottschalk R, Van Loveren H. Vandebriel RJ, et al. Among authors: gottschalk r. Toxicol Sci. 2010 Sep;117(1):81-9. doi: 10.1093/toxsci/kfq182. Epub 2010 Jun 20. Toxicol Sci. 2010. PMID: 20566472

2

Parallelogram approach using rat-human in vitro and rat in vivo toxicogenomics predicts acetaminophen-induced hepatotoxicity in humans.

Kienhuis AS, van de Poll MC, Wortelboer H, van Herwijnen M, Gottschalk R, Dejong CH, Boorsma A, Paules RS, Kleinjans JC, Stierum RH, van Delft JH. Kienhuis AS, et al. Among authors: gottschalk r. Toxicol Sci. 2009 Feb;107(2):544-52. doi: 10.1093/toxsci/kfn237. Epub 2008 Nov 12. Toxicol Sci. 2009. PMID: 19008212

3

Discrimination for genotoxic and nongenotoxic carcinogens by gene expression profiling in primary mouse hepatocytes improves with exposure time.

Mathijs K, Brauers KJ, Jennen DG, Boorsma A, van Herwijnen MH, Gottschalk RW, Kleinjans JC, van Delft JH. Mathijs K, et al. Toxicol Sci. 2009 Dec;112(2):374-84. doi: 10.1093/toxsci/kfp229. Epub 2009 Sep 21. Toxicol Sci. 2009. PMID: 19770486

4

A toxicogenomics-based parallelogram approach to evaluate the relevance of coumarin-induced responses in primary human hepatocytes in vitro for humans in vivo.

Kienhuis AS, van de Poll MC, Dejong CH, Gottschalk R, van Herwijnen M, Boorsma A, Kleinjans JC, Stierum RH, van Delft JH. Kienhuis AS, et al. Among authors: gottschalk r. Toxicol In Vitro. 2009 Sep;23(6):1163-9. doi: 10.1016/j.tiv.2009.06.005. Epub 2009 Jun 13. Toxicol In Vitro. 2009. PMID: 19527782

5

Global gene expression analysis reveals differences in cellular responses to hydroxyl- and superoxide anion radical-induced oxidative stress in caco-2 cells.

Briedé JJ, van Delft JM, de Kok TM, van Herwijnen MH, Maas LM, Gottschalk RW, Kleinjans JC. Briedé JJ, et al. Toxicol Sci. 2010 Apr;114(2):193-203. doi: 10.1093/toxsci/kfp309. Epub 2009 Dec 31. Toxicol Sci. 2010. PMID: 20044591

6

Genomic analysis suggests higher susceptibility of children to air pollution.

van Leeuwen DM, Pedersen M, Hendriksen PJ, Boorsma A, van Herwijnen MH, Gottschalk RW, Kirsch-Volders M, Knudsen LE, Srám RJ, Bajak E, van Delft JH, Kleinjans JC. van Leeuwen DM, et al. Carcinogenesis. 2008 May;29(5):977-83. doi: 10.1093/carcin/bgn065. Epub 2008 Mar 10. Carcinogenesis. 2008. PMID: 18332047

7

Differential gene expression in human peripheral blood mononuclear cells induced by cigarette smoke and its constituents.

van Leeuwen DM, Gottschalk RW, van Herwijnen MH, Moonen EJ, Kleinjans JC, van Delft JH. van Leeuwen DM, et al. Toxicol Sci. 2005 Jul;86(1):200-10. doi: 10.1093/toxsci/kfi168. Epub 2005 Apr 13. Toxicol Sci. 2005. PMID: 15829617

8

The role of glutathione in the regulation of nucleotide excision repair during oxidative stress.

Langie SA, Knaapen AM, Houben JM, van Kempen FC, de Hoon JP, Gottschalk RW, Godschalk RW, van Schooten FJ. Langie SA, et al. Toxicol Lett. 2007 Feb 5;168(3):302-9. doi: 10.1016/j.toxlet.2006.10.027. Epub 2006 Nov 16. Toxicol Lett. 2007. PMID: 17207589

9

Interactions between polycyclic aromatic hydrocarbons in binary mixtures: effects on gene expression and DNA adduct formation in precision-cut rat liver slices.

Staal YC, Pushparajah DS, van Herwijnen MH, Gottschalk RW, Maas LM, Ioannides C, van Schooten FJ, van Delft JH. Staal YC, et al. Mutagenesis. 2008 Nov;23(6):491-9. doi: 10.1093/mutage/gen041. Epub 2008 Aug 18. Mutagenesis. 2008. PMID: 18711122

10

The environmental carcinogen benzo[a]pyrene induces expression of monocyte-chemoattractant protein-1 in vascular tissue: a possible role in atherogenesis.

Knaapen AM, Curfs DM, Pachen DM, Gottschalk RW, de Winther MP, Daemen MJ, Van Schooten FJ. Knaapen AM, et al. Mutat Res. 2007 Aug 1;621(1-2):31-41. doi: 10.1016/j.mrfmmm.2006.12.010. Epub 2007 Feb 28. Mutat Res. 2007. PMID: 17376491

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