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Page 1
Food-Derived Hemorphins Cross Intestinal and Blood-Brain Barriers In Vitro.
Domenger D, Cudennec B, Kouach M, Touche V, Landry C, Lesage J, Gosselet F, Lestavel S, Goossens JF, Dhulster P, Ravallec R. Domenger D, et al. Among authors: gosselet f. Front Endocrinol (Lausanne). 2018 Apr 10;9:159. doi: 10.3389/fendo.2018.00159. eCollection 2018. Front Endocrinol (Lausanne). 2018. PMID: 29692758 Free PMC article.
Evaluation of drug-induced neurotoxicity based on metabolomics, proteomics and electrical activity measurements in complementary CNS in vitro models.
Schultz L, Zurich MG, Culot M, da Costa A, Landry C, Bellwon P, Kristl T, Hörmann K, Ruzek S, Aiche S, Reinert K, Bielow C, Gosselet F, Cecchelli R, Huber CG, Schroeder OH, Gramowski-Voss A, Weiss DG, Bal-Price A. Schultz L, et al. Among authors: gosselet f. Toxicol In Vitro. 2015 Dec 25;30(1 Pt A):138-65. doi: 10.1016/j.tiv.2015.05.016. Epub 2015 May 27. Toxicol In Vitro. 2015. PMID: 26026931 Free article.
Topical Intestinal Aminoimidazole Agonists of G-Protein-Coupled Bile Acid Receptor 1 Promote Glucagon Like Peptide-1 Secretion and Improve Glucose Tolerance.
Lasalle M, Hoguet V, Hennuyer N, Leroux F, Piveteau C, Belloy L, Lestavel S, Vallez E, Dorchies E, Duplan I, Sevin E, Culot M, Gosselet F, Boulahjar R, Herledan A, Staels B, Deprez B, Tailleux A, Charton J. Lasalle M, et al. Among authors: gosselet f. J Med Chem. 2017 May 25;60(10):4185-4211. doi: 10.1021/acs.jmedchem.6b01873. Epub 2017 May 5. J Med Chem. 2017. PMID: 28414465 Free article.
Sodium Transporters Are Involved in Lithium Influx in Brain Endothelial Cells.
Luo H, Gauthier M, Tan X, Landry C, Poupon J, Dehouck MP, Gosselet F, Perrière N, Bellivier F, Cisternino S, Declèves X. Luo H, et al. Among authors: gosselet f. Mol Pharm. 2018 Jul 2;15(7):2528-2538. doi: 10.1021/acs.molpharmaceut.8b00018. Epub 2018 Jun 14. Mol Pharm. 2018. PMID: 29874916
Efficacy Assessment of an Uncharged Reactivator of NOP-Inhibited Acetylcholinesterase Based on Tetrahydroacridine Pyridine-Aldoxime Hybrid in Mouse Compared to Pralidoxime.
Calas AG, Hanak AS, Jaffré N, Nervo A, Dias J, Rousseau C, Courageux C, Brazzolotto X, Villa P, Obrecht A, Goossens JF, Landry C, Hachani J, Gosselet F, Dehouck MP, Yerri J, Kliachyna M, Baati R, Nachon F. Calas AG, et al. Among authors: gosselet f. Biomolecules. 2020 Jun 4;10(6):858. doi: 10.3390/biom10060858. Biomolecules. 2020. PMID: 32512884 Free PMC article.
Chemoselective Hydrogenation of 6-Alkynyl-3-fluoro-2-pyridinaldoximes: Access to First-in-Class 6-Alkyl-3-Fluoro-2-pyridinaldoxime Scaffolds as New Reactivators of Sarin-Inhibited Human Acetylcholinesterase with Increased Blood-Brain Barrier Permeability.
Yerri J, Dias J, Nimmakayala MR, Razafindrainibe F, Courageux C, Gastellier AJ, Jegoux J, Coisne C, Landry C, Gosselet F, Hachani J, Goossens JF, Dehouck MP, Nachon F, Baati R. Yerri J, et al. Among authors: gosselet f. Chemistry. 2020 Nov 20;26(65):15035-15044. doi: 10.1002/chem.202002012. Epub 2020 Oct 20. Chemistry. 2020. PMID: 32633095
Beyond the Rule of 5: Impact of PEGylation with Various Polymer Sizes on Pharmacokinetic Properties, Structure-Properties Relationships of mPEGylated Small Agonists of TGR5 Receptor.
Hoguet V, Lasalle M, Maingot M, Dequirez G, Boulahjar R, Leroux F, Piveteau C, Herledan A, Biela A, Dumont J, Chávez-Talavera O, Belloy L, Duplan I, Hennuyer N, Butruille L, Lestavel S, Sevin E, Culot M, Gosselet F, Staels B, Deprez B, Tailleux A, Charton J. Hoguet V, et al. Among authors: gosselet f. J Med Chem. 2021 Feb 11;64(3):1593-1610. doi: 10.1021/acs.jmedchem.0c01774. Epub 2021 Jan 20. J Med Chem. 2021. PMID: 33470812
A New Class of Bi- and Trifunctional Sugar Oximes as Antidotes against Organophosphorus Poisoning.
Da Silva O, Probst N, Landry C, Hanak AS, Warnault P, Coisne C, Calas AG, Gosselet F, Courageux C, Gastellier AJ, Trancart M, Baati R, Dehouck MP, Jean L, Nachon F, Renard PY, Dias J. Da Silva O, et al. Among authors: gosselet f. J Med Chem. 2022 Mar 24;65(6):4649-4666. doi: 10.1021/acs.jmedchem.1c01748. Epub 2022 Mar 7. J Med Chem. 2022. PMID: 35255209 Free PMC article.
111 results