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Direct enzymatic sequencing of 5-methylcytosine at single-base resolution.
Wang T, Fowler JM, Liu L, Loo CE, Luo M, Schutsky EK, Berríos KN, DeNizio JE, Dvorak A, Downey N, Montermoso S, Pingul BY, Nasrallah M, Gosal WS, Wu H, Kohli RM. Wang T, et al. Among authors: gosal ws. Nat Chem Biol. 2023 Aug;19(8):1004-1012. doi: 10.1038/s41589-023-01318-1. Epub 2023 Jun 15. Nat Chem Biol. 2023. PMID: 37322153 Free PMC article.
Simultaneous sequencing of genetic and epigenetic bases in DNA.
Füllgrabe J, Gosal WS, Creed P, Liu S, Lumby CK, Morley DJ, Ost TWB, Vilella AJ, Yu S, Bignell H, Burns P, Charlesworth T, Fu B, Fordham H, Harding NJ, Gandelman O, Golder P, Hodson C, Li M, Lila M, Liu Y, Mason J, Mellad J, Monahan JM, Nentwich O, Palmer A, Steward M, Taipale M, Vandomme A, San-Bento RS, Singhal A, Vivian J, Wójtowicz N, Williams N, Walker NJ, Wong NCH, Yalloway GN, Holbrook JD, Balasubramanian S. Füllgrabe J, et al. Among authors: gosal ws. Nat Biotechnol. 2023 Oct;41(10):1457-1464. doi: 10.1038/s41587-022-01652-0. Epub 2023 Feb 6. Nat Biotechnol. 2023. PMID: 36747096 Free PMC article.
Hydroxymethylation profile of cell-free DNA is a biomarker for early colorectal cancer.
Walker NJ, Rashid M, Yu S, Bignell H, Lumby CK, Livi CM, Howell K, Morley DJ, Morganella S, Barrell D, Caim S, Gosal W, Füllgrabe J, Charlesworth TJ, Vasquez L, Ahdesmäki M, Eizenga J, Prabhat P, Proutski V, Murat-Onana ML, Greenwood CJ, Kirkwood L, Maisuria-Armer M, Li M, Coats E, Winfield V, MacBean L, Stock T, Tomé-Fernandez A, Chan Y, Sheikh N, Golder P, Steward M, Ost TWB, Stewart D, Vilella A, Noursalehi M, Paten B, Lucarelli D, Mason J, Ridge G, Mellad J, Shirodkar S, Balasubaramanian S, Holbrook JD. Walker NJ, et al. Sci Rep. 2022 Oct 4;12(1):16566. doi: 10.1038/s41598-022-20975-1. Sci Rep. 2022. PMID: 36195648 Free PMC article.
The spatial architecture of protein function and adaptation.
McLaughlin RN Jr, Poelwijk FJ, Raman A, Gosal WS, Ranganathan R. McLaughlin RN Jr, et al. Among authors: gosal ws. Nature. 2012 Nov 1;491(7422):138-42. doi: 10.1038/nature11500. Epub 2012 Oct 7. Nature. 2012. PMID: 23041932 Free PMC article.
Fibril fragmentation enhances amyloid cytotoxicity.
Xue WF, Hellewell AL, Gosal WS, Homans SW, Hewitt EW, Radford SE. Xue WF, et al. Among authors: gosal ws. J Biol Chem. 2009 Dec 4;284(49):34272-82. doi: 10.1074/jbc.M109.049809. Epub 2009 Oct 6. J Biol Chem. 2009. PMID: 19808677 Free PMC article.
Amyloid under the atomic force microscope.
Gosal WS, Myers SL, Radford SE, Thomson NH. Gosal WS, et al. Protein Pept Lett. 2006;13(3):261-70. doi: 10.2174/092986606775338498. Protein Pept Lett. 2006. PMID: 16515454 Review.
14 results