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GIRK1 triggers multiple cancer-related pathways in the benign mammary epithelial cell line MCF10A.
Schratter G, Scheruebel S, Langthaler S, Ester K, Pelzmann B, Ghaffari-Tabrizi-Wizsy N, Rezania S, Gorischek A, Platzer D, Zorn-Pauly K, Ahammer H, Prokesch A, Stanzer S, Devaney TTJ, Schmidt K, Jahn SW, Prassl R, Bauernhofer T, Schreibmayer W. Schratter G, et al. Among authors: gorischek a. Sci Rep. 2019 Dec 17;9(1):19277. doi: 10.1038/s41598-019-55683-w. Sci Rep. 2019. PMID: 31848385 Free PMC article.
Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner.
Rezania S, Kammerer S, Li C, Steinecker-Frohnwieser B, Gorischek A, DeVaney TT, Verheyen S, Passegger CA, Tabrizi-Wizsy NG, Hackl H, Platzer D, Zarnani AH, Malle E, Jahn SW, Bauernhofer T, Schreibmayer W. Rezania S, et al. Among authors: gorischek a. BMC Cancer. 2016 Aug 12;16:628. doi: 10.1186/s12885-016-2664-8. BMC Cancer. 2016. PMID: 27519272 Free PMC article.
Consequences of somatic mutations of GIRK1 detected in primary malign tumors on expression and function of G-protein activated, inwardly rectifying, K+ channels.
Pelzmann B, Hatab A, Scheruebel S, Langthaler S, Rienmueller T, Sokolowski A, Gorischek A, Platzer D, Zorn-Pauly K, Jahn SW, Bauernhofer T, Schreibmayer W. Pelzmann B, et al. Among authors: gorischek a. Front Oncol. 2022 Oct 31;12:998907. doi: 10.3389/fonc.2022.998907. eCollection 2022. Front Oncol. 2022. PMID: 36483038 Free PMC article.
Lipopolysaccharide-induced sepsis impairs M2R-GIRK signaling in the mouse sinoatrial node.
Shrestha N, Zorn-Pauly K, Mesirca P, Koyani CN, Wölkart G, Di Biase V, Torre E, Lang P, Gorischek A, Schreibmayer W, Arnold R, Maechler H, Mayer B, von Lewinski D, Torrente AG, Mangoni ME, Pelzmann B, Scheruebel S. Shrestha N, et al. Among authors: gorischek a. Proc Natl Acad Sci U S A. 2023 Jul 11;120(28):e2210152120. doi: 10.1073/pnas.2210152120. Epub 2023 Jul 5. Proc Natl Acad Sci U S A. 2023. PMID: 37406102 Free PMC article.
Continuous iontronic chemotherapy reduces brain tumor growth in embryonic avian in vivo models.
Handl V, Waldherr L, Arbring Sjöström T, Abrahamsson T, Seitanidou M, Erschen S, Gorischek A, Bernacka-Wojcik I, Saarela H, Tomin T, Honeder SE, Distl J, Huber W, Asslaber M, Birner-Grünberger R, Schäfer U, Berggren M, Schindl R, Patz S, Simon DT, Ghaffari-Tabrizi-Wizsy N. Handl V, et al. Among authors: gorischek a. J Control Release. 2024 Apr 11;369:668-683. doi: 10.1016/j.jconrel.2024.03.044. Online ahead of print. J Control Release. 2024. PMID: 38548064 Free article.
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