Gori SS - Search Results

1

D-DOPA Is a Potent, Orally Bioavailable, Allosteric Inhibitor of Glutamate Carboxypeptidase II.

Gori SS, Thomas AG, Pal A, Wiseman R, Ferraris DV, Gao RD, Wu Y, Alt J, Tsukamoto T, Slusher BS, Rais R. Gori SS, et al. Pharmaceutics. 2022 Sep 23;14(10):2018. doi: 10.3390/pharmaceutics14102018. Pharmaceutics. 2022. PMID: 36297453 Free PMC article.

2

Glutamine Antagonist GA-607 Causes a Dramatic Accumulation of FGAR which can be used to Monitor Target Engagement.

Alt J, Gori SS, Lemberg KM, Pal A, Veeravalli V, Wu Y, Aguilar JMH, Dash RP, Tenora L, Majer P, Sun Q, Slusher BS, Rais R. Alt J, et al. Among authors: gori ss. Curr Drug Metab. 2021;22(9):735-745. doi: 10.2174/1389200222666210831125041. Curr Drug Metab. 2021. PMID: 34488583 Free PMC article.

3

Clinical development of metabolic inhibitors for oncology.

Lemberg KM, Gori SS, Tsukamoto T, Rais R, Slusher BS. Lemberg KM, et al. Among authors: gori ss. J Clin Invest. 2022 Jan 4;132(1):e148550. doi: 10.1172/JCI148550. J Clin Invest. 2022. PMID: 34981784 Free PMC article. Review.

4

Discovery of Orally Bioavailable and Brain-Penetrable Prodrugs of the Potent nSMase2 Inhibitor DPTIP.

Pal A, Gori S, Yoo SW, Thomas AG, Wu Y, Friedman J, Tenora L, Bhasin H, Alt J, Haughey N, Slusher BS, Rais R. Pal A, et al. J Med Chem. 2022 Aug 25;65(16):11111-11125. doi: 10.1021/acs.jmedchem.2c00562. Epub 2022 Aug 5. J Med Chem. 2022. PMID: 35930706 Free PMC article.

5

Topical SCD-153, a 4-methyl itaconate prodrug, for the treatment of alopecia areata.

Tsai J, Gori S, Alt J, Tiwari S, Iyer J, Talwar R, Hinsu D, Ahirwar K, Mohanty S, Khunt C, Sutariya B, Jani K, Venkatasubbaiah V, Patel A, Meghapara J, Joshi K, Sahu R, Rana V, Nigade P, Talluri RS, Murty KVSN, Joshi K, Ramanathan V, Li A, Islam N, Snajdr I, Majer P, Rais R, Slusher BS, Garza LA. Tsai J, et al. PNAS Nexus. 2022 Dec 16;2(1):pgac297. doi: 10.1093/pnasnexus/pgac297. eCollection 2023 Jan. PNAS Nexus. 2022. PMID: 36712931 Free PMC article.

6

Synthesis and Pharmacological Characterization of a Difluorinated Analogue of Reduced Haloperidol as a Sigma-1 Receptor Ligand.

Gao RD, Taylor M, McInnis T, Chen Z, Gori SS, LaPorte HM, Siegler MA, Neisewander JL, Mach RH, Singh M, Slusher BS, Rais R, Luedtke RR, Tsukamoto T. Gao RD, et al. Among authors: gori ss. ACS Chem Neurosci. 2023 Mar 1;14(5):947-957. doi: 10.1021/acschemneuro.2c00791. Epub 2023 Feb 13. ACS Chem Neurosci. 2023. PMID: 36780706

7

Discovery of tert-Butyl Ester Based 6-Diazo-5-oxo-l-norleucine Prodrugs for Enhanced Metabolic Stability and Tumor Delivery.

Novotná K, Tenora L, Prchalová E, Paule J, Alt J, Veeravalli V, Lam J, Wu Y, Šnajdr I, Gori S, Mettu VS, Tsukamoto T, Majer P, Slusher BS, Rais R. Novotná K, et al. J Med Chem. 2023 Nov 23;66(22):15493-15510. doi: 10.1021/acs.jmedchem.3c01681. Epub 2023 Nov 10. J Med Chem. 2023. PMID: 37949450 Free PMC article.

8

Lipid Peroxidation Produces a Diverse Mixture of Saturated and Unsaturated Aldehydes in Exhaled Breath That Can Serve as Biomarkers of Lung Cancer-A Review.

Sutaria SR, Gori SS, Morris JD, Xie Z, Fu XA, Nantz MH. Sutaria SR, et al. Among authors: gori ss. Metabolites. 2022 Jun 18;12(6):561. doi: 10.3390/metabo12060561. Metabolites. 2022. PMID: 35736492 Free PMC article. Review.

9

Profiling thiol metabolites and quantification of cellular glutathione using FT-ICR-MS spectrometry.

Gori SS, Lorkiewicz P, Ehringer DS, Belshoff AC, Higashi RM, Fan TW, Nantz MH. Gori SS, et al. Anal Bioanal Chem. 2014 Jul;406(18):4371-9. doi: 10.1007/s00216-014-7810-z. Epub 2014 May 25. Anal Bioanal Chem. 2014. PMID: 24858467 Free PMC article.

10

A chemoselective, one-pot transformation of aldehydes to nitriles.

Laulhé S, Gori SS, Nantz MH. Laulhé S, et al. Among authors: gori ss. J Org Chem. 2012 Oct 19;77(20):9334-7. doi: 10.1021/jo301133y. Epub 2012 Oct 10. J Org Chem. 2012. PMID: 22928794

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