Gopal K - Search Results

1

Cardiac-Specific Deletion of Pyruvate Dehydrogenase Impairs Glucose Oxidation Rates and Induces Diastolic Dysfunction.

Gopal K, Almutairi M, Al Batran R, Eaton F, Gandhi M, Ussher JR. Gopal K, et al. Front Cardiovasc Med. 2018 Mar 6;5:17. doi: 10.3389/fcvm.2018.00017. eCollection 2018. Front Cardiovasc Med. 2018. PMID: 29560354 Free PMC article.

2

Lipotoxicity in obesity and diabetes-related cardiac dysfunction.

Zlobine I, Gopal K, Ussher JR. Zlobine I, et al. Among authors: gopal k. Biochim Biophys Acta. 2016 Oct;1861(10):1555-68. doi: 10.1016/j.bbalip.2016.02.011. Epub 2016 Feb 18. Biochim Biophys Acta. 2016. PMID: 26899197 Review.

3

Genetic and Pharmacological Inhibition of Malonyl CoA Decarboxylase Does Not Exacerbate Age-Related Insulin Resistance in Mice.

Ussher JR, Fillmore N, Keung W, Zhang L, Mori J, Sidhu VK, Fukushima A, Gopal K, Lopaschuk DG, Wagg CS, Jaswal JS, Dyck JR, Lopaschuk GD. Ussher JR, et al. Among authors: gopal k. Diabetes. 2016 Jul;65(7):1883-91. doi: 10.2337/db15-1145. Epub 2016 May 13. Diabetes. 2016. PMID: 27207536

4

Sugar-sweetened beverages and vascular function: food for thought.

Gopal K, Ussher JR. Gopal K, et al. Am J Physiol Heart Circ Physiol. 2017 Feb 1;312(2):H285-H288. doi: 10.1152/ajpheart.00783.2016. Epub 2016 Dec 30. Am J Physiol Heart Circ Physiol. 2017. PMID: 28039204 Free article. No abstract available.

5

FoxO1 regulates myocardial glucose oxidation rates via transcriptional control of pyruvate dehydrogenase kinase 4 expression.

Gopal K, Saleme B, Al Batran R, Aburasayn H, Eshreif A, Ho KL, Ma WK, Almutairi M, Eaton F, Gandhi M, Park EA, Sutendra G, Ussher JR. Gopal K, et al. Am J Physiol Heart Circ Physiol. 2017 Sep 1;313(3):H479-H490. doi: 10.1152/ajpheart.00191.2017. Epub 2017 Jul 7. Am J Physiol Heart Circ Physiol. 2017. PMID: 28687587 Free article.

6

Female offspring born to obese and insulin-resistant dams are not at increased risk for obesity and metabolic dysfunction during early development.

Aburasayn H, Al Batran R, Gopal K, Almutairi M, Eshreif A, Eaton F, Ussher JR. Aburasayn H, et al. Among authors: gopal k. Can J Physiol Pharmacol. 2018 Jan;96(1):97-102. doi: 10.1139/cjpp-2017-0371. Epub 2017 Sep 8. Can J Physiol Pharmacol. 2018. PMID: 28886253

7

Inactivation of the Glucose-Dependent Insulinotropic Polypeptide Receptor Improves Outcomes following Experimental Myocardial Infarction.

Ussher JR, Campbell JE, Mulvihill EE, Baggio LL, Bates HE, McLean BA, Gopal K, Capozzi M, Yusta B, Cao X, Ali S, Kim M, Kabir MG, Seino Y, Suzuki J, Drucker DJ. Ussher JR, et al. Among authors: gopal k. Cell Metab. 2018 Feb 6;27(2):450-460.e6. doi: 10.1016/j.cmet.2017.11.003. Epub 2017 Dec 21. Cell Metab. 2018. PMID: 29275960 Free article.

8

Skeletal muscle-specific Cre recombinase expression, controlled by the human α-skeletal actin promoter, improves glucose tolerance in mice fed a high-fat diet.

Al Batran R, Gopal K, Martin MD, Ho KL, Almutairi M, Aburasayn H, Eaton F, Campbell JE, Ussher JR. Al Batran R, et al. Among authors: gopal k. Diabetologia. 2018 Aug;61(8):1849-1855. doi: 10.1007/s00125-018-4643-x. Epub 2018 Jun 1. Diabetologia. 2018. PMID: 29858650

9

The antianginal ranolazine mitigates obesity-induced nonalcoholic fatty liver disease and increases hepatic pyruvate dehydrogenase activity.

Al Batran R, Gopal K, Aburasayn H, Eshreif A, Almutairi M, Greenwell AA, Campbell SA, Saleme B, Court EA, Eaton F, Light PE, Sutendra G, Ussher JR. Al Batran R, et al. Among authors: gopal k. JCI Insight. 2019 Jan 10;4(1):e124643. doi: 10.1172/jci.insight.124643. JCI Insight. 2019. PMID: 30626749 Free PMC article.

10

Tissue-specific regulation of p53 by PKM2 is redox dependent and provides a therapeutic target for anthracycline-induced cardiotoxicity.

Saleme B, Gurtu V, Zhang Y, Kinnaird A, Boukouris AE, Gopal K, Ussher JR, Sutendra G. Saleme B, et al. Among authors: gopal k. Sci Transl Med. 2019 Feb 6;11(478):eaau8866. doi: 10.1126/scitranslmed.aau8866. Sci Transl Med. 2019. PMID: 30728290

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