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Interference of the complex between NCS-1 and Ric8a with phenothiazines regulates synaptic function and is an approach for fragile X syndrome.
Mansilla A, Chaves-Sanjuan A, Campillo NE, Semelidou O, Martínez-González L, Infantes L, González-Rubio JM, Gil C, Conde S, Skoulakis EM, Ferrús A, Martínez A, Sánchez-Barrena MJ. Mansilla A, et al. Among authors: gonzalez rubio jm. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):E999-E1008. doi: 10.1073/pnas.1611089114. Epub 2017 Jan 24. Proc Natl Acad Sci U S A. 2017. PMID: 28119500 Free PMC article.
Deciphering the Inhibition of the Neuronal Calcium Sensor 1 and the Guanine Exchange Factor Ric8a with a Small Phenothiazine Molecule for the Rational Generation of Therapeutic Synapse Function Regulators.
Roca C, Martinez-González L, Daniel-Mozo M, Sastre J, Infantes L, Mansilla A, Chaves-Sanjuan A, González-Rubio JM, Gil C, Cañada FJ, Martinez A, Sanchez-Barrena MJ, Campillo NE. Roca C, et al. Among authors: gonzalez rubio jm. J Med Chem. 2018 Jul 26;61(14):5910-5921. doi: 10.1021/acs.jmedchem.8b00088. Epub 2018 Jul 17. J Med Chem. 2018. PMID: 29966094
Preliminary crystallographic analysis of the ankyrin-repeat domain of Arabidopsis thaliana AKT1: identification of the domain boundaries for protein crystallization.
Chaves-Sanjuán A, Sánchez-Barrena MJ, González-Rubio JM, Albert A. Chaves-Sanjuán A, et al. Among authors: gonzalez rubio jm. Acta Crystallogr F Struct Biol Commun. 2014 Apr;70(Pt 4):509-12. doi: 10.1107/S2053230X14005093. Epub 2014 Mar 25. Acta Crystallogr F Struct Biol Commun. 2014. PMID: 24699751 Free PMC article.
Structural basis of the regulatory mechanism of the plant CIPK family of protein kinases controlling ion homeostasis and abiotic stress.
Chaves-Sanjuan A, Sanchez-Barrena MJ, Gonzalez-Rubio JM, Moreno M, Ragel P, Jimenez M, Pardo JM, Martinez-Ripoll M, Quintero FJ, Albert A. Chaves-Sanjuan A, et al. Among authors: gonzalez rubio jm. Proc Natl Acad Sci U S A. 2014 Oct 21;111(42):E4532-41. doi: 10.1073/pnas.1407610111. Epub 2014 Oct 6. Proc Natl Acad Sci U S A. 2014. PMID: 25288725 Free PMC article.
Calcium-dependent oligomerization of CAR proteins at cell membrane modulates ABA signaling.
Diaz M, Sanchez-Barrena MJ, Gonzalez-Rubio JM, Rodriguez L, Fernandez D, Antoni R, Yunta C, Belda-Palazon B, Gonzalez-Guzman M, Peirats-Llobet M, Menendez M, Boskovic J, Marquez JA, Rodriguez PL, Albert A. Diaz M, et al. Among authors: gonzalez rubio jm. Proc Natl Acad Sci U S A. 2016 Jan 19;113(3):E396-405. doi: 10.1073/pnas.1512779113. Epub 2015 Dec 30. Proc Natl Acad Sci U S A. 2016. PMID: 26719420 Free PMC article.
Recognition and Activation of the Plant AKT1 Potassium Channel by the Kinase CIPK23.
Sánchez-Barrena MJ, Chaves-Sanjuan A, Raddatz N, Mendoza I, Cortés Á, Gago F, González-Rubio JM, Benavente JL, Quintero FJ, Pardo JM, Albert A. Sánchez-Barrena MJ, et al. Among authors: gonzalez rubio jm. Plant Physiol. 2020 Apr;182(4):2143-2153. doi: 10.1104/pp.19.01084. Epub 2020 Feb 3. Plant Physiol. 2020. PMID: 32015077 Free PMC article.
[Anticholinesterases in the treatment of Alzheimer's disease].
Gandía L, Alvarez RM, Hernández-Guijo JM, González-Rubio JM, de Pascual R, Rojo J, Tapia L. Gandía L, et al. Rev Neurol. 2006 Apr 16-30;42(8):471-7. Rev Neurol. 2006. PMID: 16625509 Free article. Review. Spanish.
14 results