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Nanobody-based sensors reveal a high proportion of mGlu heterodimers in the brain.
Meng J, Xu C, Lafon PA, Roux S, Mathieu M, Zhou R, Scholler P, Blanc E, Becker JAJ, Le Merrer J, González-Maeso J, Chames P, Liu J, Pin JP, Rondard P. Meng J, et al. Nat Chem Biol. 2022 Aug;18(8):894-903. doi: 10.1038/s41589-022-01050-2. Epub 2022 Jun 9. Nat Chem Biol. 2022. PMID: 35681029 Free article.
Family a GPCR heteromers in animal models.
González-Maeso J. González-Maeso J. Front Pharmacol. 2014 Oct 9;5:226. doi: 10.3389/fphar.2014.00226. eCollection 2014. Front Pharmacol. 2014. PMID: 25346690 Free PMC article. No abstract available.
Role of mGlu2 in the 5-HT2A receptor-dependent antipsychotic activity of clozapine in mice.
Hideshima KS, Hojati A, Saunders JM, On DM, de la Fuente Revenga M, Shin JM, Sánchez-González A, Dunn CM, Pais AB, Pais AC, Miles MF, Wolstenholme JT, González-Maeso J. Hideshima KS, et al. Psychopharmacology (Berl). 2018 Nov;235(11):3149-3165. doi: 10.1007/s00213-018-5015-4. Epub 2018 Sep 12. Psychopharmacology (Berl). 2018. PMID: 30209534 Free PMC article.
Identification of a serotonin/glutamate receptor complex implicated in psychosis.
González-Maeso J, Ang RL, Yuen T, Chan P, Weisstaub NV, López-Giménez JF, Zhou M, Okawa Y, Callado LF, Milligan G, Gingrich JA, Filizola M, Meana JJ, Sealfon SC. González-Maeso J, et al. Nature. 2008 Mar 6;452(7183):93-7. doi: 10.1038/nature06612. Epub 2008 Feb 24. Nature. 2008. PMID: 18297054 Free PMC article.
An upside-down binding mode to treat psychosis.
Jaster AM, González-Maeso J. Jaster AM, et al. Nat Neurosci. 2022 Jan;25(1):4-6. doi: 10.1038/s41593-021-00968-5. Nat Neurosci. 2022. PMID: 34887589 No abstract available.
113 results