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Rabbit derived VL single-domains as promising scaffolds to generate antibody-drug conjugates.
André AS, Dias JNR, Aguiar S, Nogueira S, Bule P, Carvalho JI, António JPM, Cavaco M, Neves V, Oliveira S, Vicente G, Carrapiço B, Braz BS, Rütgen B, Gano L, Correia JDG, Castanho M, Goncalves J, Gois PMP, Gil S, Tavares L, Aires-da-Silva F. André AS, et al. Among authors: goncalves j. Sci Rep. 2023 Mar 24;13(1):4837. doi: 10.1038/s41598-023-31568-x. Sci Rep. 2023. PMID: 36964198 Free PMC article.
Chimeric Small Antibody Fragments as Strategy to Deliver Therapeutic Payloads.
Aguiar S, Dias J, Manuel AM, Russo R, Gois PMP, da Silva FA, Goncalves J. Aguiar S, et al. Among authors: goncalves j. Adv Protein Chem Struct Biol. 2018;112:143-182. doi: 10.1016/bs.apcsb.2018.03.002. Epub 2018 Apr 6. Adv Protein Chem Struct Biol. 2018. PMID: 29680236 Review.
The histone deacetylase inhibitor panobinostat is a potent antitumor agent in canine diffuse large B-cell lymphoma.
Dias JNR, Aguiar SI, Pereira DM, André AS, Gano L, Correia JDG, Carrapiço B, Rütgen B, Malhó R, Peleteiro C, Goncalves J, Rodrigues CMP, Gil S, Tavares L, Aires-da-Silva F. Dias JNR, et al. Among authors: goncalves j. Oncotarget. 2018 Jun 19;9(47):28586-28598. doi: 10.18632/oncotarget.25580. eCollection 2018 Jun 19. Oncotarget. 2018. PMID: 29983882 Free PMC article.
Establishment of a bioluminescent canine B-cell lymphoma xenograft model for monitoring tumor progression and treatment response in preclinical studies.
Dias JNR, André AS, Aguiar SI, Ministro J, Oliveira J, Peleteiro MC, Rütgen B, Gano L, Correia JDG, Oliveira SS, Goncalves J, Gil S, Tavares L, Aires-da-Silva F. Dias JNR, et al. Among authors: goncalves j. PLoS One. 2018 Dec 28;13(12):e0208147. doi: 10.1371/journal.pone.0208147. eCollection 2018. PLoS One. 2018. PMID: 30592723 Free PMC article.
Highly Specific Blood-Brain Barrier Transmigrating Single-Domain Antibodies Selected by an In Vivo Phage Display Screening.
Aguiar SI, Dias JNR, André AS, Silva ML, Martins D, Carrapiço B, Castanho M, Carriço J, Cavaco M, Gaspar MM, Nobre RJ, Pereira de Almeida L, Oliveira S, Gano L, Correia JDG, Barbas C 3rd, Gonçalves J, Neves V, Aires-da-Silva F. Aguiar SI, et al. Among authors: goncalves j. Pharmaceutics. 2021 Oct 2;13(10):1598. doi: 10.3390/pharmaceutics13101598. Pharmaceutics. 2021. PMID: 34683891 Free PMC article.
Development of synthetic light-chain antibodies as novel and potent HIV fusion inhibitors.
Cunha-Santos C, Figueira TN, Borrego P, Oliveira SS, Rocha C, Couto A, Cantante C, Santos-Costa Q, Azevedo-Pereira JM, Fontes CM, Taveira N, Aires-Da-Silva F, Castanho MA, Veiga AS, Goncalves J. Cunha-Santos C, et al. Among authors: goncalves j. AIDS. 2016 Jul 17;30(11):1691-701. doi: 10.1097/QAD.0000000000001108. AIDS. 2016. PMID: 27058352
Albumin-binding domain from Streptococcus zooepidemicus protein Zag as a novel strategy to improve the half-life of therapeutic proteins.
Cantante C, Lourenço S, Morais M, Leandro J, Gano L, Silva N, Leandro P, Serrano M, Henriques AO, Andre A, Cunha-Santos C, Fontes C, Correia JDG, Aires-da-Silva F, Goncalves J. Cantante C, et al. Among authors: goncalves j. J Biotechnol. 2017 Jul 10;253:23-33. doi: 10.1016/j.jbiotec.2017.05.017. Epub 2017 May 24. J Biotechnol. 2017. PMID: 28549690
1,667 results