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Development of synthetic light-chain antibodies as novel and potent HIV fusion inhibitors.
Cunha-Santos C, Figueira TN, Borrego P, Oliveira SS, Rocha C, Couto A, Cantante C, Santos-Costa Q, Azevedo-Pereira JM, Fontes CM, Taveira N, Aires-Da-Silva F, Castanho MA, Veiga AS, Goncalves J. Cunha-Santos C, et al. Among authors: goncalves j. AIDS. 2016 Jul 17;30(11):1691-701. doi: 10.1097/QAD.0000000000001108. AIDS. 2016. PMID: 27058352
Recombinant rabbit single-chain antibodies bind to the catalytic and C-terminal domains of HIV-1 integrase protein and strongly inhibit HIV-1 replication.
da Silva FA, Li M, Rato S, Maia S, Malhó R, Warren K, Harrich D, Craigie R, Barbas C 3rd, Goncalves J. da Silva FA, et al. Among authors: goncalves j. Biotechnol Appl Biochem. 2012 Sep-Oct;59(5):353-66. doi: 10.1002/bab.1034. Epub 2012 Oct 10. Biotechnol Appl Biochem. 2012. PMID: 23586912 Free PMC article.
1,667 results