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Exercise-linked FNDC5/irisin rescues synaptic plasticity and memory defects in Alzheimer's models.
Lourenco MV, Frozza RL, de Freitas GB, Zhang H, Kincheski GC, Ribeiro FC, Gonçalves RA, Clarke JR, Beckman D, Staniszewski A, Berman H, Guerra LA, Forny-Germano L, Meier S, Wilcock DM, de Souza JM, Alves-Leon S, Prado VF, Prado MAM, Abisambra JF, Tovar-Moll F, Mattos P, Arancio O, Ferreira ST, De Felice FG. Lourenco MV, et al. Among authors: goncalves ra. Nat Med. 2019 Jan;25(1):165-175. doi: 10.1038/s41591-018-0275-4. Epub 2019 Jan 7. Nat Med. 2019. PMID: 30617325 Free PMC article.
Brain infusion of α-synuclein oligomers induces motor and non-motor Parkinson's disease-like symptoms in mice.
Fortuna JTS, Gralle M, Beckman D, Neves FS, Diniz LP, Frost PS, Barros-Aragão F, Santos LE, Gonçalves RA, Romão L, Zamberlan DC, Soares FAA, Braga C, Foguel D, Gomes FCA, De Felice FG, Ferreira ST, Clarke JR, Figueiredo CP. Fortuna JTS, et al. Among authors: goncalves ra. Behav Brain Res. 2017 Aug 30;333:150-160. doi: 10.1016/j.bbr.2017.06.047. Epub 2017 Jun 29. Behav Brain Res. 2017. PMID: 28668282
Impaired peripheral glucose homeostasis and Alzheimer's disease.
Wijesekara N, Gonçalves RA, De Felice FG, Fraser PE. Wijesekara N, et al. Among authors: goncalves ra. Neuropharmacology. 2018 Jul 1;136(Pt B):172-181. doi: 10.1016/j.neuropharm.2017.11.027. Epub 2017 Nov 21. Neuropharmacology. 2018. PMID: 29169962 Review.
Behavioral Abnormalities in Knockout and Humanized Tau Mice.
Gonçalves RA, Wijesekara N, Fraser PE, De Felice FG. Gonçalves RA, et al. Front Endocrinol (Lausanne). 2020 Mar 12;11:124. doi: 10.3389/fendo.2020.00124. eCollection 2020. Front Endocrinol (Lausanne). 2020. PMID: 32226410 Free PMC article.
Pro-inflammatory interleukin-6 signaling links cognitive impairments and peripheral metabolic alterations in Alzheimer's disease.
Lyra E Silva NM, Gonçalves RA, Pascoal TA, Lima-Filho RAS, Resende EPF, Vieira ELM, Teixeira AL, de Souza LC, Peny JA, Fortuna JTS, Furigo IC, Hashiguchi D, Miya-Coreixas VS, Clarke JR, Abisambra JF, Longo BM, Donato J Jr, Fraser PE, Rosa-Neto P, Caramelli P, Ferreira ST, De Felice FG. Lyra E Silva NM, et al. Among authors: goncalves ra. Transl Psychiatry. 2021 Apr 28;11(1):251. doi: 10.1038/s41398-021-01349-z. Transl Psychiatry. 2021. PMID: 33911072 Free PMC article.
110 results