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Pleiotropic effects of GIP on islet function involve osteopontin.
Lyssenko V, Eliasson L, Kotova O, Pilgaard K, Wierup N, Salehi A, Wendt A, Jonsson A, De Marinis YZ, Berglund LM, Taneera J, Balhuizen A, Hansson O, Osmark P, Dunér P, Brøns C, Stancáková A, Kuusisto J, Bugliani M, Saxena R, Ahlqvist E, Kieffer TJ, Tuomi T, Isomaa B, Melander O, Sonestedt E, Orho-Melander M, Nilsson P, Bonetti S, Bonadonna R, Miccoli R, Delprato S, Marchetti P, Madsbad S, Poulsen P, Vaag A, Laakso M, Gomez MF, Groop L. Lyssenko V, et al. Among authors: gomez mf. Diabetes. 2011 Sep;60(9):2424-33. doi: 10.2337/db10-1532. Epub 2011 Aug 1. Diabetes. 2011. PMID: 21810601 Free PMC article.
Deletion of the G protein-coupled receptor 30 impairs glucose tolerance, reduces bone growth, increases blood pressure, and eliminates estradiol-stimulated insulin release in female mice.
Mårtensson UE, Salehi SA, Windahl S, Gomez MF, Swärd K, Daszkiewicz-Nilsson J, Wendt A, Andersson N, Hellstrand P, Grände PO, Owman C, Rosen CJ, Adamo ML, Lundquist I, Rorsman P, Nilsson BO, Ohlsson C, Olde B, Leeb-Lundberg LM. Mårtensson UE, et al. Among authors: gomez mf. Endocrinology. 2009 Feb;150(2):687-98. doi: 10.1210/en.2008-0623. Epub 2008 Oct 9. Endocrinology. 2009. PMID: 18845638
Nuclear factor of activated T cells regulates osteopontin expression in arterial smooth muscle in response to diabetes-induced hyperglycemia.
Nilsson-Berglund LM, Zetterqvist AV, Nilsson-Ohman J, Sigvardsson M, González Bosc LV, Smith ML, Salehi A, Agardh E, Fredrikson GN, Agardh CD, Nilsson J, Wamhoff BR, Hultgårdh-Nilsson A, Gomez MF. Nilsson-Berglund LM, et al. Among authors: gomez mf. Arterioscler Thromb Vasc Biol. 2010 Feb;30(2):218-24. doi: 10.1161/ATVBAHA.109.199299. Epub 2009 Dec 3. Arterioscler Thromb Vasc Biol. 2010. PMID: 19965778 Free PMC article.
Link between GIP and osteopontin in adipose tissue and insulin resistance.
Ahlqvist E, Osmark P, Kuulasmaa T, Pilgaard K, Omar B, Brøns C, Kotova O, Zetterqvist AV, Stancáková A, Jonsson A, Hansson O, Kuusisto J, Kieffer TJ, Tuomi T, Isomaa B, Madsbad S, Gomez MF, Poulsen P, Laakso M, Degerman E, Pihlajamäki J, Wierup N, Vaag A, Groop L, Lyssenko V. Ahlqvist E, et al. Among authors: gomez mf. Diabetes. 2013 Jun;62(6):2088-94. doi: 10.2337/db12-0976. Epub 2013 Jan 24. Diabetes. 2013. PMID: 23349498 Free PMC article.
152 results