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Identification and targeting of a unique NaV1.7 domain driving chronic pain.
Gomez K, Stratton HJ, Duran P, Loya S, Tang C, Calderon-Rivera A, François-Moutal L, Khanna M, Madura CL, Luo S, McKiver B, Choi E, Ran D, Boinon L, Perez-Miller S, Damaj MI, Moutal A, Khanna R. Gomez K, et al. Proc Natl Acad Sci U S A. 2023 Aug 8;120(32):e2217800120. doi: 10.1073/pnas.2217800120. Epub 2023 Jul 27. Proc Natl Acad Sci U S A. 2023. PMID: 37498871 Free PMC article.
The Natural Flavonoid Naringenin Elicits Analgesia through Inhibition of NaV1.8 Voltage-Gated Sodium Channels.
Zhou Y, Cai S, Moutal A, Yu J, Gómez K, Madura CL, Shan Z, Pham NYN, Serafini MJ, Dorame A, Scott DD, François-Moutal L, Perez-Miller S, Patek M, Khanna M, Khanna R. Zhou Y, et al. Among authors: gomez k. ACS Chem Neurosci. 2019 Dec 18;10(12):4834-4846. doi: 10.1021/acschemneuro.9b00547. Epub 2019 Nov 21. ACS Chem Neurosci. 2019. PMID: 31697467
Cdk5-Dependent Phosphorylation of CaV3.2 T-Type Channels: Possible Role in Nerve Ligation-Induced Neuropathic Allodynia and the Compound Action Potential in Primary Afferent C Fibers.
Gomez K, Calderón-Rivera A, Sandoval A, González-Ramírez R, Vargas-Parada A, Ojeda-Alonso J, Granados-Soto V, Delgado-Lezama R, Felix R. Gomez K, et al. J Neurosci. 2020 Jan 8;40(2):283-296. doi: 10.1523/JNEUROSCI.0181-19.2019. Epub 2019 Nov 19. J Neurosci. 2020. PMID: 31744861 Free PMC article.
1-O-Acetylgeopyxin A, a derivative of a fungal metabolite, blocks tetrodotoxin-sensitive voltage-gated sodium, calcium channels and neuronal excitability which correlates with inhibition of neuropathic pain.
Zhou Y, Cai S, Gomez K, Wijeratne EMK, Ji Y, Bellampalli SS, Luo S, Moutal A, Gunatilaka AAL, Khanna R. Zhou Y, et al. Among authors: gomez k. Mol Brain. 2020 May 11;13(1):73. doi: 10.1186/s13041-020-00616-2. Mol Brain. 2020. PMID: 32393368 Free PMC article.
A modulator of the low-voltage-activated T-type calcium channel that reverses HIV glycoprotein 120-, paclitaxel-, and spinal nerve ligation-induced peripheral neuropathies.
Cai S, Tuohy P, Ma C, Kitamura N, Gomez K, Zhou Y, Ran D, Bellampalli SS, Yu J, Luo S, Dorame A, Yen Ngan Pham N, Molnar G, Streicher JM, Patek M, Perez-Miller S, Moutal A, Wang J, Khanna R. Cai S, et al. Among authors: gomez k. Pain. 2020 Nov;161(11):2551-2570. doi: 10.1097/j.pain.0000000000001955. Pain. 2020. PMID: 32541387 Free PMC article.
Putative roles of SLC7A5 (LAT1) transporter in pain.
Alles SRA, Gomez K, Moutal A, Khanna R. Alles SRA, et al. Among authors: gomez k. Neurobiol Pain. 2020 Jun 30;8:100050. doi: 10.1016/j.ynpai.2020.100050. eCollection 2020 Aug-Dec. Neurobiol Pain. 2020. PMID: 32715162 Free PMC article. Review.
The role of cyclin-dependent kinase 5 in neuropathic pain.
Gomez K, Vallecillo TGM, Moutal A, Perez-Miller S, Delgado-Lezama R, Felix R, Khanna R. Gomez K, et al. Pain. 2020 Dec;161(12):2674-2689. doi: 10.1097/j.pain.0000000000002027. Pain. 2020. PMID: 32773603 Free PMC article. Review.
SARS-CoV-2 Spike protein co-opts VEGF-A/Neuropilin-1 receptor signaling to induce analgesia.
Moutal A, Martin LF, Boinon L, Gomez K, Ran D, Zhou Y, Stratton HJ, Cai S, Luo S, Gonzalez KB, Perez-Miller S, Patwardhan A, Ibrahim MM, Khanna R. Moutal A, et al. Among authors: gomez k. bioRxiv [Preprint]. 2020 Sep 14:2020.07.17.209288. doi: 10.1101/2020.07.17.209288. bioRxiv. 2020. PMID: 32869019 Free PMC article. Updated. Preprint.
339 results