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Longitudinal proteomic analysis of severe COVID-19 reveals survival-associated signatures, tissue-specific cell death, and cell-cell interactions.
Filbin MR, Mehta A, Schneider AM, Kays KR, Guess JR, Gentili M, Fenyves BG, Charland NC, Gonye ALK, Gushterova I, Khanna HK, LaSalle TJ, Lavin-Parsons KM, Lilley BM, Lodenstein CL, Manakongtreecheep K, Margolin JD, McKaig BN, Rojas-Lopez M, Russo BC, Sharma N, Tantivit J, Thomas MF, Gerszten RE, Heimberg GS, Hoover PJ, Lieb DJ, Lin B, Ngo D, Pelka K, Reyes M, Smillie CS, Waghray A, Wood TE, Zajac AS, Jennings LL, Grundberg I, Bhattacharyya RP, Parry BA, Villani AC, Sade-Feldman M, Hacohen N, Goldberg MB. Filbin MR, et al. Among authors: goldberg mb. Cell Rep Med. 2021 May 18;2(5):100287. doi: 10.1016/j.xcrm.2021.100287. Epub 2021 May 3. Cell Rep Med. 2021. PMID: 33969320 Free PMC article.
Systematic analysis of bacterial effector-postsynaptic density 95/disc large/zonula occludens-1 (PDZ) domain interactions demonstrates Shigella OspE protein promotes protein kinase C activation via PDLIM proteins.
Yi CR, Allen JE, Russo B, Lee SY, Heindl JE, Baxt LA, Herrera BB, Kahoud E, MacBeath G, Goldberg MB. Yi CR, et al. Among authors: goldberg mb. J Biol Chem. 2014 Oct 24;289(43):30101-13. doi: 10.1074/jbc.M114.595868. Epub 2014 Sep 8. J Biol Chem. 2014. PMID: 25124035 Free PMC article.
Intermediate filaments enable pathogen docking to trigger type 3 effector translocation.
Russo BC, Stamm LM, Raaben M, Kim CM, Kahoud E, Robinson LR, Bose S, Queiroz AL, Herrera BB, Baxt LA, Mor-Vaknin N, Fu Y, Molina G, Markovitz DM, Whelan SP, Goldberg MB. Russo BC, et al. Among authors: goldberg mb. Nat Microbiol. 2016 Mar 7;1:16025. doi: 10.1038/nmicrobiol.2016.25. Nat Microbiol. 2016. PMID: 27572444 Free PMC article.
Rapid identification and phylogenetic classification of diverse bacterial pathogens in a multiplexed hybridization assay targeting ribosomal RNA.
Bhattacharyya RP, Walker M, Boykin R, Son SS, Liu J, Hachey AC, Ma P, Wu L, Choi K, Cummins KC, Benson M, Skerry J, Ryu H, Wong SY, Goldberg MB, Han J, Pierce VM, Cosimi LA, Shoresh N, Livny J, Beechem J, Hung DT. Bhattacharyya RP, et al. Among authors: goldberg mb. Sci Rep. 2019 Mar 14;9(1):4516. doi: 10.1038/s41598-019-40792-3. Sci Rep. 2019. PMID: 30872641 Free PMC article.
An immune-cell signature of bacterial sepsis.
Reyes M, Filbin MR, Bhattacharyya RP, Billman K, Eisenhaure T, Hung DT, Levy BD, Baron RM, Blainey PC, Goldberg MB, Hacohen N. Reyes M, et al. Among authors: goldberg mb. Nat Med. 2020 Mar;26(3):333-340. doi: 10.1038/s41591-020-0752-4. Epub 2020 Feb 17. Nat Med. 2020. PMID: 32066974 Free PMC article.
Induction of a regulatory myeloid program in bacterial sepsis and severe COVID-19.
Reyes M, Filbin MR, Bhattacharyya RP, Sonny A, Mehta A, Billman K, Kays KR, Pinilla-Vera M, Benson ME, Cosimi LA, Hung DT, Levy BD, Villani AC, Sade-Feldman M, Baron RM, Goldberg MB, Blainey PC, Hacohen N. Reyes M, et al. Among authors: goldberg mb. bioRxiv [Preprint]. 2020 Sep 2:2020.09.02.280180. doi: 10.1101/2020.09.02.280180. bioRxiv. 2020. PMID: 32908980 Free PMC article. Updated. Preprint.
Viral epitope profiling of COVID-19 patients reveals cross-reactivity and correlates of severity.
Shrock E, Fujimura E, Kula T, Timms RT, Lee IH, Leng Y, Robinson ML, Sie BM, Li MZ, Chen Y, Logue J, Zuiani A, McCulloch D, Lelis FJN, Henson S, Monaco DR, Travers M, Habibi S, Clarke WA, Caturegli P, Laeyendecker O, Piechocka-Trocha A, Li JZ, Khatri A, Chu HY; MGH COVID-19 Collection & Processing Team; Villani AC, Kays K, Goldberg MB, Hacohen N, Filbin MR, Yu XG, Walker BD, Wesemann DR, Larman HB, Lederer JA, Elledge SJ. Shrock E, et al. Among authors: goldberg mb. Science. 2020 Nov 27;370(6520):eabd4250. doi: 10.1126/science.abd4250. Epub 2020 Sep 29. Science. 2020. PMID: 32994364 Free PMC article.
184 results