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Novel Cephalosporins Selectively Active on Nonreplicating Mycobacterium tuberculosis.
Gold B, Smith R, Nguyen Q, Roberts J, Ling Y, Lopez Quezada L, Somersan S, Warrier T, Little D, Pingle M, Zhang D, Ballinger E, Zimmerman M, Dartois V, Hanson P, Mitscher LA, Porubsky P, Rogers S, Schoenen FJ, Nathan C, Aubé J. Gold B, et al. J Med Chem. 2016 Jul 14;59(13):6027-44. doi: 10.1021/acs.jmedchem.5b01833. Epub 2016 Jun 17. J Med Chem. 2016. PMID: 27144688 Free PMC article.
Selective killing of nonreplicating mycobacteria.
Bryk R, Gold B, Venugopal A, Singh J, Samy R, Pupek K, Cao H, Popescu C, Gurney M, Hotha S, Cherian J, Rhee K, Ly L, Converse PJ, Ehrt S, Vandal O, Jiang X, Schneider J, Lin G, Nathan C. Bryk R, et al. Among authors: gold b. Cell Host Microbe. 2008 Mar 13;3(3):137-45. doi: 10.1016/j.chom.2008.02.003. Cell Host Microbe. 2008. PMID: 18329613 Free PMC article.
Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials.
Gold B, Pingle M, Brickner SJ, Shah N, Roberts J, Rundell M, Bracken WC, Warrier T, Somersan S, Venugopal A, Darby C, Jiang X, Warren JD, Fernandez J, Ouerfelli O, Nuermberger EL, Cunningham-Bussel A, Rath P, Chidawanyika T, Deng H, Realubit R, Glickman JF, Nathan CF. Gold B, et al. Proc Natl Acad Sci U S A. 2012 Oct 2;109(40):16004-11. doi: 10.1073/pnas.1214188109. Epub 2012 Sep 10. Proc Natl Acad Sci U S A. 2012. PMID: 23012453 Free PMC article.
Benzimidazole-based compounds kill Mycobacterium tuberculosis.
Gong Y, Somersan Karakaya S, Guo X, Zheng P, Gold B, Ma Y, Little D, Roberts J, Warrier T, Jiang X, Pingle M, Nathan CF, Liu G. Gong Y, et al. Among authors: gold b. Eur J Med Chem. 2014 Mar 21;75:336-53. doi: 10.1016/j.ejmech.2014.01.039. Epub 2014 Jan 31. Eur J Med Chem. 2014. PMID: 24556148
N-methylation of a bactericidal compound as a resistance mechanism in Mycobacterium tuberculosis.
Warrier T, Kapilashrami K, Argyrou A, Ioerger TR, Little D, Murphy KC, Nandakumar M, Park S, Gold B, Mi J, Zhang T, Meiler E, Rees M, Somersan-Karakaya S, Porras-De Francisco E, Martinez-Hoyos M, Burns-Huang K, Roberts J, Ling Y, Rhee KY, Mendoza-Losana A, Luo M, Nathan CF. Warrier T, et al. Among authors: gold b. Proc Natl Acad Sci U S A. 2016 Aug 2;113(31):E4523-30. doi: 10.1073/pnas.1606590113. Epub 2016 Jul 18. Proc Natl Acad Sci U S A. 2016. PMID: 27432954 Free PMC article.
829 results