Gokce O - Search Results

1

CD8⁺ T cells induce interferon-responsive oligodendrocytes and microglia in white matter aging.

Kaya T, Mattugini N, Liu L, Ji H, Cantuti-Castelvetri L, Wu J, Schifferer M, Groh J, Martini R, Besson-Girard S, Kaji S, Liesz A, Gokce O, Simons M. Kaya T, et al. Among authors: gokce o. Nat Neurosci. 2022 Nov;25(11):1446-1457. doi: 10.1038/s41593-022-01183-6. Epub 2022 Oct 24. Nat Neurosci. 2022. PMID: 36280798 Free PMC article.

2

Decreased striatal RGS2 expression is neuroprotective in Huntington's disease (HD) and exemplifies a compensatory aspect of HD-induced gene regulation.

Seredenina T, Gokce O, Luthi-Carter R. Seredenina T, et al. Among authors: gokce o. PLoS One. 2011;6(7):e22231. doi: 10.1371/journal.pone.0022231. Epub 2011 Jul 14. PLoS One. 2011. PMID: 21779398 Free PMC article.

3

SIRT2 inhibition achieves neuroprotection by decreasing sterol biosynthesis.

Luthi-Carter R, Taylor DM, Pallos J, Lambert E, Amore A, Parker A, Moffitt H, Smith DL, Runne H, Gokce O, Kuhn A, Xiang Z, Maxwell MM, Reeves SA, Bates GP, Neri C, Thompson LM, Marsh JL, Kazantsev AG. Luthi-Carter R, et al. Among authors: gokce o. Proc Natl Acad Sci U S A. 2010 Apr 27;107(17):7927-32. doi: 10.1073/pnas.1002924107. Epub 2010 Apr 8. Proc Natl Acad Sci U S A. 2010. PMID: 20378838 Free PMC article.

4

Short-term striatal gene expression responses to brain-derived neurotrophic factor are dependent on MEK and ERK activation.

Gokce O, Runne H, Kuhn A, Luthi-Carter R. Gokce O, et al. PLoS One. 2009;4(4):e5292. doi: 10.1371/journal.pone.0005292. Epub 2009 Apr 23. PLoS One. 2009. PMID: 19390590 Free PMC article.

5

Dysregulation of gene expression in primary neuron models of Huntington's disease shows that polyglutamine-related effects on the striatal transcriptome may not be dependent on brain circuitry.

Runne H, Régulier E, Kuhn A, Zala D, Gokce O, Perrin V, Sick B, Aebischer P, Déglon N, Luthi-Carter R. Runne H, et al. Among authors: gokce o. J Neurosci. 2008 Sep 24;28(39):9723-31. doi: 10.1523/JNEUROSCI.3044-08.2008. J Neurosci. 2008. PMID: 18815258 Free PMC article.

6

Single-Cell mRNA Profiling Reveals Cell-Type-Specific Expression of Neurexin Isoforms.

Fuccillo MV, Földy C, Gökce Ö, Rothwell PE, Sun GL, Malenka RC, Südhof TC. Fuccillo MV, et al. Among authors: gokce o. Neuron. 2015 Jul 15;87(2):326-40. doi: 10.1016/j.neuron.2015.06.028. Neuron. 2015. PMID: 26182417 Free PMC article.

7

Diminished activity-dependent brain-derived neurotrophic factor expression underlies cortical neuron microcircuit hypoconnectivity resulting from exposure to mutant huntingtin fragments.

Gambazzi L, Gokce O, Seredenina T, Katsyuba E, Runne H, Markram H, Giugliano M, Luthi-Carter R. Gambazzi L, et al. Among authors: gokce o. J Pharmacol Exp Ther. 2010 Oct;335(1):13-22. doi: 10.1124/jpet.110.167551. Epub 2010 Jul 12. J Pharmacol Exp Ther. 2010. PMID: 20624994

8

The ratio of monomeric to aggregated forms of Abeta40 and Abeta42 is an important determinant of amyloid-beta aggregation, fibrillogenesis, and toxicity.

Jan A, Gokce O, Luthi-Carter R, Lashuel HA. Jan A, et al. Among authors: gokce o. J Biol Chem. 2008 Oct 17;283(42):28176-89. doi: 10.1074/jbc.M803159200. Epub 2008 Aug 11. J Biol Chem. 2008. PMID: 18694930 Free PMC article.

9

Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors.

Rothwell PE, Fuccillo MV, Maxeiner S, Hayton SJ, Gokce O, Lim BK, Fowler SC, Malenka RC, Südhof TC. Rothwell PE, et al. Among authors: gokce o. Cell. 2014 Jul 3;158(1):198-212. doi: 10.1016/j.cell.2014.04.045. Cell. 2014. PMID: 24995986 Free PMC article.

10

Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.

Zhang B, Chen LY, Liu X, Maxeiner S, Lee SJ, Gokce O, Südhof TC. Zhang B, et al. Among authors: gokce o. Neuron. 2015 Aug 19;87(4):781-96. doi: 10.1016/j.neuron.2015.07.020. Neuron. 2015. PMID: 26291161 Free PMC article.

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