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Rapid Bladder Interleukin-10 Synthesis in Response to Uropathogenic Escherichia coli Is Part of a Defense Strategy Triggered by the Major Bacterial Flagellar Filament FliC and Contingent on TLR5.
Acharya D, Sullivan MJ, Duell BL, Goh KGK, Katupitiya L, Gosling D, Chamoun MN, Kakkanat A, Chattopadhyay D, Crowley M, Crossman DK, Schembri MA, Ulett GC. Acharya D, et al. Among authors: goh kgk. mSphere. 2019 Nov 27;4(6):e00545-19. doi: 10.1128/mSphere.00545-19. mSphere. 2019. PMID: 31776239 Free PMC article.
Restriction of chronic Escherichia coli urinary tract infection depends upon T cell-derived interleukin-17, a deficiency of which predisposes to flagella-driven bacterial persistence.
Chamoun MN, Sullivan MJ, Goh KGK, Acharya D, Ipe DS, Katupitiya L, Gosling D, Peters KM, Sweet MJ, Sester DP, Schembri MA, Ulett GC. Chamoun MN, et al. Among authors: goh kgk. FASEB J. 2020 Nov;34(11):14572-14587. doi: 10.1096/fj.202000760R. Epub 2020 Sep 9. FASEB J. 2020. PMID: 32901999
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