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Discovery of potent and selective reversible Bruton's tyrosine kinase inhibitors.
Qiu H, Ali Z, Bender A, Caldwell R, Chen YY, Fang Z, Gardberg A, Glaser N, Goettsche A, Goutopoulos A, Grenningloh R, Hanschke B, Head J, Johnson T, Jones C, Jones R, Kulkarni S, Maurer C, Morandi F, Neagu C, Poetzsch S, Potnick J, Schmidt R, Roe K, Viacava Follis A, Wing C, Zhu X, Sherer B. Qiu H, et al. Among authors: goettsche a. Bioorg Med Chem. 2021 Jun 15;40:116163. doi: 10.1016/j.bmc.2021.116163. Epub 2021 Apr 20. Bioorg Med Chem. 2021. PMID: 33932711
Avoiding N-nitrosodimethylamine formation in metformin pharmaceuticals by limiting dimethylamine and nitrite.
Schlingemann J, Boucley C, Hickert S, Bourasseau L, Walker M, Celdran C, Chemarin T, Pegues C, Fritzsche M, Keitel J, Goettsche A, Seegel M, Leicht S, Guessregen B, Reifenberg P, Wetzel S, Müller T, Schooren F, Schuster T, Liebhold M, Kirsch A, Krueger P, Saal C, Mouton B, Masanes S. Schlingemann J, et al. Among authors: goettsche a. Int J Pharm. 2022 May 25;620:121740. doi: 10.1016/j.ijpharm.2022.121740. Epub 2022 Apr 11. Int J Pharm. 2022. PMID: 35421534 Free article.
NDMA analytics in metformin products: Comparison of methods and pitfalls.
Fritzsche M, Blom G, Keitel J, Goettsche A, Seegel M, Leicht S, Guessregen B, Hickert S, Reifenberg P, Cimelli A, Baranowski R, Desmartin E, Barrau E, Harrison M, Bristow T, O'Neill N, Kirsch A, Krueger P, Saal C, Mouton B, Schlingemann J. Fritzsche M, et al. Among authors: goettsche a. Eur J Pharm Sci. 2022 Jan 1;168:106026. doi: 10.1016/j.ejps.2021.106026. Epub 2021 Sep 29. Eur J Pharm Sci. 2022. PMID: 34597792 Free article.
Validation of treatment strategies for enterohaemorrhagic Escherichia coli O104:H4 induced haemolytic uraemic syndrome: case-control study.
Menne J, Nitschke M, Stingele R, Abu-Tair M, Beneke J, Bramstedt J, Bremer JP, Brunkhorst R, Busch V, Dengler R, Deuschl G, Fellermann K, Fickenscher H, Gerigk C, Goettsche A, Greeve J, Hafer C, Hagenmüller F, Haller H, Herget-Rosenthal S, Hertenstein B, Hofmann C, Lang M, Kielstein JT, Klostermeier UC, Knobloch J, Kuehbacher M, Kunzendorf U, Lehnert H, Manns MP, Menne TF, Meyer TN, Michael C, Münte T, Neumann-Grutzeck C, Nuernberger J, Pavenstaedt H, Ramazan L, Renders L, Repenthin J, Ries W, Rohr A, Rump LC, Samuelsson O, Sayk F, Schmidt BM, Schnatter S, Schöcklmann H, Schreiber S, von Seydewitz CU, Steinhoff J, Stracke S, Suerbaum S, van de Loo A, Vischedyk M, Weissenborn K, Wellhöner P, Wiesner M, Zeissig S, Büning J, Schiffer M, Kuehbacher T; EHEC-HUS consortium. Menne J, et al. Among authors: goettsche a. BMJ. 2012 Jul 19;345:e4565. doi: 10.1136/bmj.e4565. BMJ. 2012. PMID: 22815429 Free PMC article.