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Sibiriline, a new small chemical inhibitor of receptor-interacting protein kinase 1, prevents immune-dependent hepatitis.
Le Cann F, Delehouzé C, Leverrier-Penna S, Filliol A, Comte A, Delalande O, Desban N, Baratte B, Gallais I, Piquet-Pellorce C, Faurez F, Bonnet M, Mettey Y, Goekjian P, Samson M, Vandenabeele P, Bach S, Dimanche-Boitrel MT. Le Cann F, et al. Among authors: goekjian p. FEBS J. 2017 Sep;284(18):3050-3068. doi: 10.1111/febs.14176. Epub 2017 Aug 11. FEBS J. 2017. PMID: 28715128 Free article.
6E11, a highly selective inhibitor of Receptor-Interacting Protein Kinase 1, protects cells against cold hypoxia-reoxygenation injury.
Delehouzé C, Leverrier-Penna S, Le Cann F, Comte A, Jacquard-Fevai M, Delalande O, Desban N, Baratte B, Gallais I, Faurez F, Bonnet MC, Hauteville M, Goekjian PG, Thuillier R, Favreau F, Vandenabeele P, Hauet T, Dimanche-Boitrel MT, Bach S. Delehouzé C, et al. Among authors: goekjian pg. Sci Rep. 2017 Oct 10;7(1):12931. doi: 10.1038/s41598-017-12788-4. Sci Rep. 2017. PMID: 29018243 Free PMC article.
Nigratine as dual inhibitor of necroptosis and ferroptosis regulated cell death.
Delehouzé C, Comte A, Leon-Icaza SA, Cougoule C, Hauteville M, Goekjian P, Bulinski JC, Dimanche-Boitrel MT, Meunier E, Rousselot M, Bach S. Delehouzé C, et al. Among authors: goekjian p. Sci Rep. 2022 Mar 24;12(1):5118. doi: 10.1038/s41598-022-09019-w. Sci Rep. 2022. PMID: 35332201 Free PMC article.
An Optimized Workflow for the Discovery of New Antimicrobial Compounds Targeting Bacterial RNA Polymerase Complex Formation.
Caputo A, Sartini S, Levati E, Minato I, Elisi GM, Di Stasi A, Guillou C, Goekjian PG, Garcia P, Gueyrard D, Bach S, Comte A, Ottonello S, Rivara S, Montanini B. Caputo A, et al. Among authors: goekjian pg. Antibiotics (Basel). 2022 Oct 21;11(10):1449. doi: 10.3390/antibiotics11101449. Antibiotics (Basel). 2022. PMID: 36290107 Free PMC article.
Targeting RNA structure in SMN2 reverses spinal muscular atrophy molecular phenotypes.
Garcia-Lopez A, Tessaro F, Jonker HRA, Wacker A, Richter C, Comte A, Berntenis N, Schmucki R, Hatje K, Petermann O, Chiriano G, Perozzo R, Sciarra D, Konieczny P, Faustino I, Fournet G, Orozco M, Artero R, Metzger F, Ebeling M, Goekjian P, Joseph B, Schwalbe H, Scapozza L. Garcia-Lopez A, et al. Among authors: goekjian p. Nat Commun. 2018 May 23;9(1):2032. doi: 10.1038/s41467-018-04110-1. Nat Commun. 2018. PMID: 29795225 Free PMC article.
Protein kinase C inhibitors as novel anticancer drugs.
Goekjian PG, Jirousek MR. Goekjian PG, et al. Expert Opin Investig Drugs. 2001 Dec;10(12):2117-40. doi: 10.1517/13543784.10.12.2117. Expert Opin Investig Drugs. 2001. PMID: 11772309 Review.
Identification of non-ATP-competitive α-carboline inhibitors of the anaplastic lymphoma kinase.
Mologni L, Orsato A, Zambon A, Tardy S, Bisson WH, Schneider C, Ceccon M, Viltadi M, D'Attoma J, Pannilunghi S, Vece V, Gueyrard D, Bertho J, Scapozza L, Goekjian P, Gambacorti-Passerini C. Mologni L, et al. Among authors: goekjian p. Eur J Med Chem. 2022 Aug 5;238:114488. doi: 10.1016/j.ejmech.2022.114488. Epub 2022 May 25. Eur J Med Chem. 2022. PMID: 35665691
24 results