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A stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.
LaBelle JL, Katz SG, Bird GH, Gavathiotis E, Stewart ML, Lawrence C, Fisher JK, Godes M, Pitter K, Kung AL, Walensky LD. LaBelle JL, et al. Among authors: godes m. J Clin Invest. 2012 Jun;122(6):2018-31. doi: 10.1172/JCI46231. Epub 2012 May 24. J Clin Invest. 2012. PMID: 22622039 Free PMC article.
Direct inhibition of oncogenic KRAS by hydrocarbon-stapled SOS1 helices.
Leshchiner ES, Parkhitko A, Bird GH, Luccarelli J, Bellairs JA, Escudero S, Opoku-Nsiah K, Godes M, Perrimon N, Walensky LD. Leshchiner ES, et al. Among authors: godes m. Proc Natl Acad Sci U S A. 2015 Feb 10;112(6):1761-6. doi: 10.1073/pnas.1413185112. Epub 2015 Jan 26. Proc Natl Acad Sci U S A. 2015. PMID: 25624485 Free PMC article.
A stapled p53 helix overcomes HDMX-mediated suppression of p53.
Bernal F, Wade M, Godes M, Davis TN, Whitehead DG, Kung AL, Wahl GM, Walensky LD. Bernal F, et al. Among authors: godes m. Cancer Cell. 2010 Nov 16;18(5):411-22. doi: 10.1016/j.ccr.2010.10.024. Cancer Cell. 2010. PMID: 21075307 Free PMC article.
Hydrocarbon-Stitched Peptide Agonists of Glucagon-Like Peptide-1 Receptor.
Bird GH, Fu A, Escudero S, Godes M, Opoku-Nsiah K, Wales TE, Cameron MD, Engen JR, Danial NN, Walensky LD. Bird GH, et al. Among authors: godes m. ACS Chem Biol. 2020 Jun 19;15(6):1340-1348. doi: 10.1021/acschembio.0c00308. Epub 2020 May 27. ACS Chem Biol. 2020. PMID: 32348108 Free PMC article.
Generation of Potent and Stable GLP-1 Analogues Via "Serine Ligation".
Levine PM, Craven TW, Li X, Balana AT, Bird GH, Godes M, Salveson PJ, Erickson PW, Lamb M, Ahlrichs M, Murphy M, Ogohara C, Said MY, Walensky LD, Pratt MR, Baker D. Levine PM, et al. Among authors: godes m. ACS Chem Biol. 2022 Apr 15;17(4):804-809. doi: 10.1021/acschembio.2c00075. Epub 2022 Mar 23. ACS Chem Biol. 2022. PMID: 35319882 Free PMC article.
70 results